Caspases, Initiator [iniciační kaspasy]
topical
3
- Terms
-
apikální kaspázy
iniciační kaspázy
kaspasy iniciační
-
Initiator Caspases
Persistent link
https://www.medvik.cz/link/D053471
Definition
A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzyme. The pro-domain regions contain protein-protein interaction motifs that can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS; DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated, the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.
- DUI
- D053471 MeSH Browser
- CUI
- M0491612
- Previous indexing
- Cysteine Proteinases (1997-1998); Caspases (1999-2006)
- History note
- 2007
- Public note
- 2007
Combination
- antagonists & inhibitors
- Caspase Inhibitors
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- BI
- biosynthesis 0
- BL
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- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
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- EC
- economics 0
- GE
- genetics 0
- HI
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- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 2
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
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...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.277.656.262.500.126.775
Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
1
D08.811.277.656.300.200.126.775
Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
1