Nod Signaling Adaptor Proteins [signální adaptorové proteiny Nod]
- Terms
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signální adaptorové proteiny NOD-LRR
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NOD Leucine-Rich Repeat Proteins
NOD-LRR Signaling Adaptor Proteins
Nuclear-Binding Oligomerization Domain Proteins
Nucleotide Oligomerization Domain Proteins
Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance.
- DUI
- D053472 MeSH Browser
- CUI
- M0493381
- History note
- 2007
- Public note
- 2007
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