B7-H1 Antigen [antigeny CD274]

topical
248
Terms

Antigens, CD274
B7-H1 Immune Costimulatory Protein
B7H1 Immune Costimulatory Protein
CD274 Antigen
PD-L1 Costimulatory Protein
PD-L1 Protein
Programmed Cell Death 1 Ligand 1
Programmed Cell Death 1 Ligand 1 Protein
Programmed Death Ligand 1

Persistent link   https://www.medvik.cz/link/D060890
Definition

An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.

DUI
D060890 MeSH Browser
CUI
M0555734
Previous indexing
Antigens, CD (2007-2011); Antigens, CD80 (2001-2006); Blood Proteins (2001-2005)
History note
2018 (2007)
Public note
2018; see ANTIGENS, CD274 2012-2017

Allowable subheadings

AD
administration & dosage 5
AE
adverse effects 4
AG
agonists
AN
analysis 13
AI
antagonists & inhibitors 90
BI
biosynthesis 4
BL
blood 3
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification 1
DF
deficiency
DE
drug effects 16
EC
economics
GE
genetics 25
HI
history
IM
immunology 32
IP
isolation & purification 3
ME
metabolism 41
PK
pharmacokinetics 3
PD
pharmacology 3
PH
physiology 7
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 21
TO
toxicity 1
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.465 Immune Checkpoint Proteins 7
D12.776.465.500 B7-2 Antigen 14
D12.776.465.625 B7-H1 Antigen 248
D12.776.465.750 CD40 Antigens 18
D12.776.465.782 CTLA-4 Antigen 192
D12.776.465.798 Hepatitis A Virus Cellular Receptor 2 7
D12.776.465.806 Lymphocyte Activation Gene 3 Protein 1
D12.776.465.813 OX40 Ligand 1
D12.776.465.829 Programmed Cell Death 1 Ligand 2 Protein 15
D12.776.465.844 Programmed Cell Death 1 Receptor 293
D12.776.465.875 Receptors, OX40 3
D12.776.467 Intercellular Signaling Peptides and Proteins 156
D12.776.467.150 B7 Antigens 3
D12.776.467.150.100 B7-1 Antigen 25
D12.776.467.150.200 B7-2 Antigen 14
D12.776.467.150.300 B7-H1 Antigen 248
D12.776.467.150.500 Inducible T-Cell Co-Stimulator Ligand
D12.776.467.150.800 Programmed Cell Death 1 Ligand 2 Protein 15
D12.776.467.150.900 V-Set Domain-Containing T-Cell Activation Inhibitor 1
D12.776.543 Membrane Proteins 850
D12.776.543.095 B7 Antigens 3
D12.776.543.095.100 B7-1 Antigen 25
D12.776.543.095.200 B7-2 Antigen 14
D12.776.543.095.300 B7-H1 Antigen 248
D12.776.543.095.500 Inducible T-Cell Co-Stimulator Ligand
D12.776.543.095.800 Programmed Cell Death 1 Ligand 2 Protein 15
D12.776.543.095.900 V-Set Domain-Containing T-Cell Activation Inhibitor 1
D23 Biological Factors 143
D23.050 Antigens 1 131
D23.050.301 Antigens, Surface 174
D23.050.301.285 B7 Antigens 3
D23.050.301.285.100 B7-1 Antigen 25
D23.050.301.285.200 B7-2 Antigen 14
D23.050.301.285.400 B7-H1 Antigen 248
D23.050.301.285.500 Inducible T-Cell Co-Stimulator Ligand
D23.050.301.285.800 Programmed Cell Death 1 Ligand 2 Protein 15
D23.050.301.285.900 V-Set Domain-Containing T-Cell Activation Inhibitor 1
D23.529 Intercellular Signaling Peptides and Proteins 156
D23.529.168 B7 Antigens 3
D23.529.168.100 B7-1 Antigen 25
D23.529.168.200 B7-2 Antigen 14
D23.529.168.300 B7-H1 Antigen 248
D23.529.168.500 Inducible T-Cell Co-Stimulator Ligand
D23.529.168.800 Programmed Cell Death 1 Ligand 2 Protein 15
D23.529.168.900 V-Set Domain-Containing T-Cell Activation Inhibitor 1

CD274 protein, human Chemical MeSH Browser

Cd274 protein, mouse Chemical MeSH Browser

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