Geminin [geminin]

topical
1
Persistent link   https://www.medvik.cz/link/D064248
Definition

Geminin inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME.

DUI
D064248 MeSH Browser
CUI
M0580547
Previous indexing
Cell Cycle Proteins (1998-2013)
History note
2014