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Autor
Antignani, Pier Luigi 1 Blinc, Aleš 1 Catalano, Mariella 1 Cífková, Renata 1 Fras, Zlatko 1 Höbaus, Clemens 1 Ježovnik, Mateja Kaja 1 Jug, Borut 1 Marie Maier, Jeanette Anne 1 Nemcsik, Janos 1 Nicolaides, Andrew N 1 Paraskevas, Kosmas I 1 Poredoš, Pavel 1 Poredoš, Peter 1 Reiner, Željko 1 Schernthaner, Gerit Holger 1 Wohlfahrt, Peter 1 Šabovič, Mišo 1
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Pracoviště
Center for Cardiovascular Prevention ... 1 Department for Metabolic Diseases Uni... 1 Department of Anaesthesiology and Per... 1 Department of Family Medicine Semmelw... 1 Department of Medicine 2 Charles Univ... 1 Department of Vascular Disease Univer... 1 Department of Vascular Surgery Centra... 1 Department of Vascular Surgery Imperi... 1 Faculty of Medicine University of Lju... 1 Health Service of Zugló Department of... 1 The Medical University of Vienna Depa... 1 The University of Milan Department of... 1 The University of Milan Research Cent... 1 The University of Texas Health Scienc... 1 University of Nicosia Medical School ... 1 Vascular Centre Nuova Villa Claudia V... 1 Vascular Screening and Diagnostic Cen... 1
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Autor
Antignani, Pier Luigi 1 Blinc, Aleš 1 Catalano, Mariella 1 Cífková, Renata 1 Fras, Zlatko 1 Höbaus, Clemens 1 Ježovnik, Mateja Kaja 1 Jug, Borut 1 Marie Maier, Jeanette Anne 1 Nemcsik, Janos 1 Nicolaides, Andrew N 1 Paraskevas, Kosmas I 1 Poredoš, Pavel 1 Poredoš, Peter 1 Reiner, Željko 1 Schernthaner, Gerit Holger 1 Wohlfahrt, Peter 1 Šabovič, Mišo 1
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Pracoviště
Center for Cardiovascular Prevention ... 1 Department for Metabolic Diseases Uni... 1 Department of Anaesthesiology and Per... 1 Department of Family Medicine Semmelw... 1 Department of Medicine 2 Charles Univ... 1 Department of Vascular Disease Univer... 1 Department of Vascular Surgery Centra... 1 Department of Vascular Surgery Imperi... 1 Faculty of Medicine University of Lju... 1 Health Service of Zugló Department of... 1 The Medical University of Vienna Depa... 1 The University of Milan Department of... 1 The University of Milan Research Cent... 1 The University of Texas Health Scienc... 1 University of Nicosia Medical School ... 1 Vascular Centre Nuova Villa Claudia V... 1 Vascular Screening and Diagnostic Cen... 1
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- Poredoš, Pavel
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Cífková, Renata
Autor Cífková, Renata Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer University Hospital, Kateřinská 1660/32, 121 08, Nové Město, Czech Republic Department of Medicine II, Charles University in Prague, First Faculty of Medicine, Kateřinská 1660/32, 121 08, Nové Město, Czech Republic. Electronic address: renata.cifkova@ftn.cz
- Marie Maier, Jeanette Anne
- Nemcsik, Janos
- Šabovič, Mišo
- Jug, Borut
- Ježovnik, Mateja Kaja
- Schernthaner, Gerit Holger
- Antignani, Pier Luigi
- Catalano, Mariella
PubMed
35398698
DOI
10.1016/j.atherosclerosis.2022.03.030
Knihovny.cz E-zdroje
Atherosclerosis has a long preclinical phase, and the risk of cardiovascular (CV) events may be high in asymptomatic subjects. Conventional risk factors provide information for the statistical probability of developing CV events, but they lack precision in asymptomatic subjects. This review aims to summarize the role of some widely publicized indicators of early atherosclerosis in predicting CV events. The earliest measurable indicator of the atherosclerotic process is endothelial dysfunction, measured by flow-mediated dilation (FMD) of the brachial artery. However, reduced FMD is a stronger predictor of future CV events in patients with existing CV disease than in apparently healthy persons. Alternatively, measurement of carotid artery intima-media thickness does not improve the predictive value of risk factor scores, while detection of asymptomatic atherosclerotic plaques in carotid or common femoral arteries by ultrasound indicates high CV risk. Coronary calcium is a robust and validated help in the estimation of vascular changes and risk, which may improve risk stratification beyond traditional risk factors with relatively low radiation exposure. Arterial stiffness of the aorta, measured as the carotid-femoral pulse wave velocity is an independent marker of CV risk at the population level, but it is not recommended as a routine procedure because of measurement difficulties. Low ankle-brachial index (ABI) indicates flow-limiting atherosclerosis in the lower limbs and indicates high CV risk, while normal ABI does not rule out advanced asymptomatic atherosclerosis. Novel circulating biomarkers are associated with the atherosclerotic process. However, because of limited specificity, their ability to improve risk classification at present remains low.
- MeSH
- analýza pulzové vlny MeSH
- arteriae carotides diagnostické zobrazování MeSH
- ateroskleróza * diagnóza MeSH
- intimomediální šíře tepenné stěny MeSH
- kardiovaskulární nemoci * diagnóza MeSH
- konsensus MeSH
- lidé MeSH
- rizikové faktory MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
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