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Autor
Abedi-Ardekani, Behnoush 1 Albanes, Demetrius 1 Anderson, Garnet L 1 Andreotti, Gabriella 1 Anema, John G 1 Baglietto, Laura 1 Banks, Rosamonde E 1 Barman, Poulami 1 Basta-Jovanovic, Gordana 1 Bencko, Vladimir 1 Benhamou, Simone 1 Besse, Celine 1 Black, Amanda 1 Blanche, Helene 1 Boeing, Heiner 1 Boland, Anne 1 Brennan, Paul 1 Brown, Kevin M 1 Bruinsma, Fiona 1 Burdette, Laurie 1
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Pracoviště
1st Faculty of Medicine Institute of ... 1 2nd Faculty of Medicine Institute of ... 1 American Cancer Society Atlanta Georg... 1 Brigham and Women's Hospital and VA B... 1 Cancer Epidemiology Centre Cancer Cou... 1 Cancer Prevention Program Fred Hutchi... 1 Carol Davila University of Medicine a... 1 CeRePP Tenon Hospital 75020 Paris Fra... 1 Center 'Bioengineering' of the Russia... 1 Centre National de Genotypage Institu... 1 Centre National de Genotypage Institu... 1 Centre de Recherche en Épidémiologie ... 1 Centre de Recherche en Épidémiologie ... 1 Clinical Center of Serbia Clinic of U... 1 Dana Farber Cancer Institute Boston M... 1 Department of Cancer Epidemiology and... 1 Department of Community Medicine Facu... 1 Department of Computational Biology S... 1 Department of Epidemiology Division o... 1 Department of Epidemiology German Ins... 1
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Autor
Abedi-Ardekani, Behnoush 1 Albanes, Demetrius 1 Anderson, Garnet L 1 Andreotti, Gabriella 1 Anema, John G 1 Baglietto, Laura 1 Banks, Rosamonde E 1 Barman, Poulami 1 Basta-Jovanovic, Gordana 1 Bencko, Vladimir 1 Benhamou, Simone 1 Besse, Celine 1 Black, Amanda 1 Blanche, Helene 1 Boeing, Heiner 1 Boland, Anne 1 Brennan, Paul 1 Brown, Kevin M 1 Bruinsma, Fiona 1 Burdette, Laurie 1
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Pracoviště
1st Faculty of Medicine Institute of ... 1 2nd Faculty of Medicine Institute of ... 1 American Cancer Society Atlanta Georg... 1 Brigham and Women's Hospital and VA B... 1 Cancer Epidemiology Centre Cancer Cou... 1 Cancer Prevention Program Fred Hutchi... 1 Carol Davila University of Medicine a... 1 CeRePP Tenon Hospital 75020 Paris Fra... 1 Center 'Bioengineering' of the Russia... 1 Centre National de Genotypage Institu... 1 Centre National de Genotypage Institu... 1 Centre de Recherche en Épidémiologie ... 1 Centre de Recherche en Épidémiologie ... 1 Clinical Center of Serbia Clinic of U... 1 Dana Farber Cancer Institute Boston M... 1 Department of Cancer Epidemiology and... 1 Department of Community Medicine Facu... 1 Department of Computational Biology S... 1 Department of Epidemiology Division o... 1 Department of Epidemiology German Ins... 1
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Free Medical Journals od 2010
Nature Open Access od 2010-12-01
PubMed Central od 2012
Europe PubMed Central od 2012
ProQuest Central od 2010-01-01
Open Access Digital Library od 2015-01-01
Open Access Digital Library od 2015-01-01
Medline Complete (EBSCOhost) od 2012-11-01
Health & Medicine (ProQuest) od 2010-01-01
ROAD: Directory of Open Access Scholarly Resources od 2010
PubMed
28598434
DOI
10.1038/ncomms15724
Knihovny.cz E-zdroje
Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10-10), 3p22.1 (rs67311347, P=2.5 × 10-8), 3q26.2 (rs10936602, P=8.8 × 10-9), 8p21.3 (rs2241261, P=5.8 × 10-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10-8), 11q22.3 (rs74911261, P=2.1 × 10-10) and 14q24.2 (rs4903064, P=2.2 × 10-24). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility.
- MeSH
- běloši genetika MeSH
- celogenomová asociační studie * MeSH
- dospělí MeSH
- fenotyp MeSH
- genetická predispozice k nemoci * MeSH
- genetické lokusy MeSH
- jednonukleotidový polymorfismus MeSH
- karcinom z renálních buněk genetika MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- nádory ledvin genetika MeSH
- senioři MeSH
- zárodečné mutace MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- metaanalýza MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
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