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Autor
Bradna, Pavel 1 Dvorackova, Stepanka 1 Fenclova, Zdenka 1 Klusackova, Pavlina 1 Kolesnikova, Viktoriia 1 Kostejn, Martin 1 Lischkova, Lucie 1 Navratil, Tomas 1 Ondracek, Jakub 1 Ondrackova, Lucie 1 Pelclova, Daniela 1 Pohanka, Miroslav 1 Rossnerova, Andrea 1 Schwarz, Jaroslav 1 Vlckova, Stepanka 1 Zdimal, Vladimir 1
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Autor
Bradna, Pavel 1 Dvorackova, Stepanka 1 Fenclova, Zdenka 1 Klusackova, Pavlina 1 Kolesnikova, Viktoriia 1 Kostejn, Martin 1 Lischkova, Lucie 1 Navratil, Tomas 1 Ondracek, Jakub 1 Ondrackova, Lucie 1 Pelclova, Daniela 1 Pohanka, Miroslav 1 Rossnerova, Andrea 1 Schwarz, Jaroslav 1 Vlckova, Stepanka 1 Zdimal, Vladimir 1
- Pracoviště
- Formát
- Publikační typ
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Vlastník
PubMed
38275177
DOI
10.2217/nnm-2023-0207
Knihovny.cz E-zdroje
Aim: To find a practical biomonitoring method for researchers exposed to nanoparticles causing oxidative stress. Methods: In a continuation of a study in 2016-2018, biological samples (plasma, urine and exhaled breath condensate [EBC]) were collected in 2019-2020 from 43 researchers (13.8 ± 3.0 years of exposure) and 45 controls. Antioxidant status was assessed using glutathione (GSH) and ferric-reducing antioxidant power, while oxidative stress was measured as thiobarbituric acid reactive substances, all using spectrophotometric methods. Researchers' personal nanoparticle exposure was monitored. Results: Plasma GSH was elevated in researchers both before and after exposure (p < 0.01); postexposure plasma GSH correlated with nanoparticle exposure, and GSH in EBC increased. Conclusion: The results suggest adaptation to chronic exposure to nanoparticles, as monitored by plasma and EBC GSH.
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Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.