BACKGROUND: Cardiac implantable electronic device (CIED) implantation rates as well as the clinical and procedural characteristics and outcomes in patients with known active coronavirus disease 2019 (COVID-19) are unknown. OBJECTIVE: The purpose of this study was to gather information regarding CIED procedures during active COVID-19, performed with personal protective equipment, based on an international survey. METHODS: Fifty-three centers from 13 countries across 4 continents provided information on 166 patients with known active COVID-19 who underwent a CIED procedure. RESULTS: The CIED procedure rate in 133,655 hospitalized COVID-19 patients ranged from 0 to 16.2 per 1000 patients (P <.001). Most devices were implanted due to high-degree/complete atrioventricular block (112 [67.5%]) or sick sinus syndrome (31 [18.7%]). Of the 166 patients in the study survey, the 30-day complication rate was 13.9% and the 180-day mortality rate was 9.6%. One patient had a fatal outcome as a direct result of the procedure. Differences in patient and procedural characteristics and outcomes were found between Europe and North America. An older population (76.6 vs 66 years; P <.001) with a nonsignificant higher complication rate (16.5% vs 7.7%; P = .2) was observed in Europe vs North America, whereas higher rates of critically ill patients (33.3% vs 3.3%; P <.001) and mortality (26.9% vs 5%; P = .002) were observed in North America vs Europe. CONCLUSION: CIED procedure rates during known active COVID-19 disease varied greatly, from 0 to 16.2 per 1000 hospitalized COVID-19 patients worldwide. Patients with active COVID-19 infection who underwent CIED implantation had high complication and mortality rates. Operators should take these risks into consideration before proceeding with CIED implantation in active COVID-19 patients.

• MeSH
• Atrioventricular Block * epidemiology   therapy   MeSH
• Global Health statistics & numerical data   MeSH
• COVID-19 * diagnosis   epidemiology   therapy   MeSH
• Defibrillators, Implantable statistics & numerical data   MeSH
• Outcome Assessment, Health Care MeSH
• Prosthesis Implantation * adverse effects   instrumentation   mortality   MeSH
• Pacemaker, Artificial statistics & numerical data   MeSH
• Comorbidity MeSH
• Infection Control * instrumentation   methods   organization & administration   MeSH
• Middle Aged MeSH
• Humans MeSH
• Mortality MeSH
• Postoperative Complications * diagnosis   mortality   MeSH
• Surveys and Questionnaires MeSH
• Risk Factors MeSH
• SARS-CoV-2 isolation & purification   MeSH
• Aged MeSH
• Sick Sinus Syndrome * epidemiology   therapy   MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH