The transcriptional activity of RHOA, SEMA3B, and CKAP2 genes was assessed in blood samples of leukaemia patients and healthy donors. In the blood of healthy donors, RHOA and CKAP2 gene expression was not detected, and low SEMA3B gene expression was observed. Significant elevation of expression of all the three genes was shown in the case of acute myelogenous leukaemia. In cases of remission of acute lymphoblastic leukaemia and myelodysplastic syndrome, no expression of all three genes was detected. The long isoform of the CKAP2 gene was highly expressed in most analysed types of leukaemia.

• MeSH
• cytoskeletální proteiny krev   genetika   MeSH
• dospělí MeSH
• leukemie krev   genetika   MeSH
• lidé MeSH
• membránové glykoproteiny krev   genetika   MeSH
• pilotní projekty MeSH
• protein - isoformy krev   genetika   MeSH
• regulace genové exprese u leukemie * MeSH
• rhoA protein vázající GTP krev   genetika   MeSH
• semaforiny krev   genetika   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH