Cross-linking mass spectrometry (MS) has substantially matured as a method over the past 2 decades through parallel development in multiple labs, demonstrating its applicability to protein structure determination, conformation analysis, and mapping protein interactions in complex mixtures. Cross-linking MS has become a much-appreciated and routinely applied tool, especially in structural biology. Therefore, it is timely that the community commits to the development of methodological and reporting standards. This white paper builds on an open process comprising a number of events at community conferences since 2015 and identifies aspects of Cross-linking MS for which guidelines should be developed as part of a Cross-linking MS standards initiative.
- MeSH
- hmotnostní spektrometrie přístrojové vybavení metody normy MeSH
- konformace proteinů MeSH
- lidé MeSH
- mapování interakce mezi proteiny metody MeSH
- mezinárodní spolupráce MeSH
- proteiny ultrastruktura MeSH
- proteomika přístrojové vybavení metody normy MeSH
- reagencia zkříženě vázaná chemie MeSH
- reprodukovatelnost výsledků MeSH
- směrnice jako téma MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- kongresy MeSH
- práce podpořená grantem MeSH