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Author
Anker, Stefan D 1 Bocchi, Edimar 1 Brueckmann, Martina 1 Brunner-La Rocca, Hans-Peter 1 Butler, Javed 1 Böhm, Michael 1 Carson, Peter 1 Choi, Dong-Ju 1 Chopra, Vijay 1 Chuquiure, Eduardo 1 Cotton, Daniel 1 Filippatos, Gerasimos 1 Giannetti, Nadia 1 Gonzalez Juanatey, Jose R 1 Jamal, Waheed 1 Janssens, Stefan 1 Januzzi, James 1 Kaul, Sanjay 1 Kimura, Karen 1 Merkely, Bela 1
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Boehringer Ingelheim Pharmaceuticals Ridgefi... 1 Fleni Institute and Hospital El Cruce Nestor... 1 From Baylor Heart and Vascular Institute Bay... 1 Fuwai Hospital National Center for Cardiovas... 1 Heart Institute São Paulo University Medical... 1 Imperial College all in the United Kingdom 1 Internal Cardiology University Hospital Brno... 1 Maastricht Heart and Vascular Center Maastri... 1 National and Kapodistrian University of Athe... 1 Victorian Heart Institute and Monash Univers... 1 Washington DC Veterans Affairs Medical Cente... 1 the Cardiology Department University Hospita... 1 the Cardiovascular Department Papa Giovanni ... 1 the Center for Heart Diseases Wrocław Medica... 1 the Department of Cardiology Cedars Sinai Me... 1 the Department of Cardiology Max Super Speci... 1 the Department of Cardiology University Hosp... 1 the Department of Cardiology University Hosp... 1 the Department of Cardiology and Berlin Inst... 1 the Department of Cardiovascular Medicine Ky... 1
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Packer, Milton
Author Packer, Milton From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Anker, Stefan D
Author Anker, Stefan D From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Butler, Javed
Author Butler, Javed From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Filippatos, Gerasimos
Author Filippatos, Gerasimos From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Pocock, Stuart J
Author Pocock, Stuart J From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Carson, Peter
Author Carson, Peter From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Januzzi, James
Author Januzzi, James From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Verma, Subodh
Author Verma, Subodh From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Tsutsui, Hiroyuki
Author Tsutsui, Hiroyuki From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
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Brueckmann, Martina
Author Brueckmann, Martina From Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas (M.P.) Imperial College (M.P.) and the Department of Medical Statistics, London School of Hygiene and Tropical Medicine (S.J.P.), London, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow (N.S.), and the Department of Cardiovascular Sciences, University of Leicester and National Institute for Health Research Biomedical Research Centre, Glenfield Hospital, Leicester (I.S.) - all in the United Kingdom the Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies, German Center for Cardiovascular Research Partner Site Berlin, Charité Universitätsmedizin, Berlin (S.D.A.), Boehringer Ingelheim International, Ingelheim (M. Brueckmann, W.J.), Faculty of Medicine Mannheim, University of Heidelberg, Mannheim (M. Brueckmann), Boehringer Ingelheim Pharma, Biberach (C.Z.), Klinik für Innere Medizin III, Saarland University, Homburg-Saar (M. Böhm), and the Department of Medicine, University Hospital of Würzburg, Würzburg (C.W.) - all in Germany the Department of Medicine, University of Mississippi School of Medicine, Jackson (J.B.) National and Kapodistrian University of Athens School of Medicine, Athens University Hospital Attikon, Athens (G.F.) Washington DC Veterans Affairs Medical Center, Washington DC (P.C.) the Division of Cardiology, Harvard Medical School and Massachusetts General Hospital, Boston (J.J.) the Division of Cardiac Surgery, St. Michael's Hospital, University of Toronto, Toronto (S.V.), Boehringer Ingelheim Canada, Burlington, ON (K.K.), and the Division of Cardiology, McGill University and Health Centre, Montreal (N.G.) - all in Canada the Department of Cardiovascular Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan (H.T.) Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (J. Schnee, D.C.) Heart Institute, São Paulo University Medical School, São Paulo (E.B.) the Department of Medicine, Seoul National University, Seoul, South Korea (D.-J.C.) the Department of Cardiology, Max Super Speciality Hospital, Saket, New Delhi, India (V.C.) the Department of Clinical Cardiology, National Institute of Cardiology, Mexico City (E.C.) the Department of Cardiology, University Hospital Gasthuisberg of Leuven, Leuven, Belgium (S.J.) Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z.) the Cardiology Department, University Hospital, Santiago de Compostela, Spain (J.R.G.J.) the Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles (S.K.) Maastricht Heart and Vascular Center, Maastricht, the Netherlands (H.P.B.-L.R.) the Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M.) Victorian Heart Institute and Monash University, Melbourne, VIC, Australia (S.J.N.) Fleni Institute and Hospital El Cruce-Nestor Kirchner, Buenos Aires (S.P.) the Department of Medicine, Wayne State and Central Michigan Universities, Detroit (I.P.) the Center for Heart Diseases, Wrocław Medical University, Wrocław, Poland (P.P.) the Cardiovascular Department, Papa Giovanni XXIII Hospital, Bergamo (M.S.), and the Department of Clinical and Experimental Medicine, University of Pisa, Pisa (S.T.) - both in Italy the Department of Cardiology, University Hospital Jean Minjoz, Besançon (M.-F.S.), and Université de Lorraine, INSERM Investigation Network Initiative-Cardiovascular and Renal Clinical Trialists, Centre Hospitalier Régional Universitaire, Nancy (F.Z.) - both in France and Internal Cardiology, University Hospital Brno, Brno, Czech Republic (J. Spinar)
NLK
ProQuest Central
from 1980-01-03 to 3 months ago
Nursing & Allied Health Database (ProQuest)
from 1980-01-03 to 3 months ago
Health & Medicine (ProQuest)
from 1980-01-03 to 3 months ago
Family Health Database (ProQuest)
from 1980-01-03 to 3 months ago
Psychology Database (ProQuest)
from 1980-01-03 to 3 months ago
Health Management Database (ProQuest)
from 1980-01-03 to 3 months ago
Public Health Database (ProQuest)
from 1980-01-03 to 3 months ago
PubMed
32865377
DOI
10.1056/nejmoa2022190
Knihovny.cz E-resources
BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure in patients regardless of the presence or absence of diabetes. More evidence is needed regarding the effects of these drugs in patients across the broad spectrum of heart failure, including those with a markedly reduced ejection fraction. METHODS: In this double-blind trial, we randomly assigned 3730 patients with class II, III, or IV heart failure and an ejection fraction of 40% or less to receive empagliflozin (10 mg once daily) or placebo, in addition to recommended therapy. The primary outcome was a composite of cardiovascular death or hospitalization for worsening heart failure. RESULTS: During a median of 16 months, a primary outcome event occurred in 361 of 1863 patients (19.4%) in the empagliflozin group and in 462 of 1867 patients (24.7%) in the placebo group (hazard ratio for cardiovascular death or hospitalization for heart failure, 0.75; 95% confidence interval [CI], 0.65 to 0.86; P<0.001). The effect of empagliflozin on the primary outcome was consistent in patients regardless of the presence or absence of diabetes. The total number of hospitalizations for heart failure was lower in the empagliflozin group than in the placebo group (hazard ratio, 0.70; 95% CI, 0.58 to 0.85; P<0.001). The annual rate of decline in the estimated glomerular filtration rate was slower in the empagliflozin group than in the placebo group (-0.55 vs. -2.28 ml per minute per 1.73 m2 of body-surface area per year, P<0.001), and empagliflozin-treated patients had a lower risk of serious renal outcomes. Uncomplicated genital tract infection was reported more frequently with empagliflozin. CONCLUSIONS: Among patients receiving recommended therapy for heart failure, those in the empagliflozin group had a lower risk of cardiovascular death or hospitalization for heart failure than those in the placebo group, regardless of the presence or absence of diabetes. (Funded by Boehringer Ingelheim and Eli Lilly; EMPEROR-Reduced ClinicalTrials.gov number, NCT03057977.).
- MeSH
- Benzhydryl Compounds adverse effects therapeutic use MeSH
- Renal Insufficiency, Chronic complications MeSH
- Diabetes Mellitus, Type 2 complications MeSH
- Double-Blind Method MeSH
- Sodium-Glucose Transporter 2 Inhibitors adverse effects therapeutic use MeSH
- Glucosides adverse effects therapeutic use MeSH
- Glomerular Filtration Rate drug effects MeSH
- Hospitalization statistics & numerical data MeSH
- Cardiovascular Diseases mortality prevention & control MeSH
- Middle Aged MeSH
- Humans MeSH
- Disease Progression MeSH
- Proportional Hazards Models MeSH
- Aged MeSH
- Heart Failure complications drug therapy physiopathology MeSH
- Stroke Volume MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Multicenter Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Randomized Controlled Trial MeSH
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