phase-locked loop
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Slow-wave synchronous acoustic stimulation is a promising research and therapeutic tool. It is essential to clearly understand the principles of the synchronization methods, to know their performances and limitations, and, most importantly, to have a clear picture of the effect of stimulation on slow-wave activity (SWA). This paper covers the mentioned and currently missing parts of knowledge that are essential for the appropriate development of the method itself and future applications. Artificially streamed real sleep EEG data were used to quantitatively compare the two currently used real-time methods: the phase-locking loop (PLL) and the fixed-step stimulus in our own implementation. The fixed-step stimulation method was concluded to be more reliable and practically applicable compared to the PLL method. The sleep experiment with chronic insomnia patients in our sleep laboratory was analyzed in order to precisely characterize the effect of sound stimulation during deep sleep. We found that there is a significant phase synchronization of delta waves, which were shown to be the most sensitive metric of the effect of acoustic stimulation compared to commonly used averaged signal and power analyses. This finding may change the understanding of the effect and function of the SWA stimulation described in the literature.
- MeSH
- akustická stimulace MeSH
- elektroencefalografie MeSH
- lidé MeSH
- spánek pomalých vln * MeSH
- spánek MeSH
- techniky fyzikální terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
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1st ed. 209 s. ; 30 cm
... Chains -- Can Fold into Regular Structures Such as the Alpha -- Helix, the Beta Sheet, and Turns and Loops ... ... Polypeptide Strands 58 -- 3.3.3 Polypeptide Chains Can Change Direction by -- Making Reverse Turns and Loops ... ... Visualization of Proteins in the Cell 103 -- 4.4 Peptides Can Be Synthesized by Automated -- Solid-Phase ... ... Sanger Dideoxy Method) 146 -- 6.1.4 DNA Probes and Genes Can Be Synthesized by -- Automated Solid - Phase ... ... NTP-Dependent Enzymes 254 -- 9.4.3 ATP Binding Induces Large Conformational -- Changes 255 -- 9.4.4 P-Loop ...
5th ed. xvii, 974 s. : il., tab., grafy ; 32 cm
... One-to-One Relationships, 54 One-to-Many Relationships, 55 Many-to-Many Relationships, 57 Cycles, 58 Loops ... ... 8.5 Automatic Error Handling: The Whenever Statement, 383 -- 8.6 Transaction Processing Statements: Lock ... ... Vertical Partitioning, 678 -- 14.4 Replicating a Database, 679 The Master/Slave Technique, 679 The Two-Phase ...
1st ed. ix, 781 s.
