Tapeworms of the genus Proteocephalus Weinland, 1858 (Cestoda: Proteocephalidae) are common and widespread intestinal parasites of whitefish (Coregonus spp., Salmonidae: Coregoninae). Previous taxonomic studies, based solely on morphology and inconsistently fixed specimens, concluded that all salmoniform fish, including whitefish, are parasitised by a single euryxenous and highly polymorphic species, Proteocephalus longicollis (Zeder, 1800). However, recent molecular phylogenetic analyses have revealed the existence of several species specific to individual genera or even species of salmoniform fish. In this study, Proteocephalus fallax La Rue, 1911 is redescribed based on newly collected and genetically characterised specimens from several Coregonus species in Switzerland, the type locality of the species, and in Norway. This cestode was previously synonymised with P. exiguus La Rue, 1911, a parasite of whitefish in North America, but the two species are not closely related. Proteocephalus fallax differs from P. exiguus in its larger body size, wider proglottids, shorter cirrus sac and broader scolex. In addition, the other Proteocephalus species described in whitefish are briefly discussed, with comments on their validity, host range and distribution.
- MeSH
- Cestoda * klasifikace anatomie a histologie izolace a purifikace MeSH
- cestodózy * veterinární parazitologie MeSH
- fylogeneze * MeSH
- nemoci ryb * parazitologie MeSH
- Salmonidae * parazitologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Norsko MeSH
- Švýcarsko MeSH
- MeSH
- farmaceutické služby MeSH
- lidé MeSH
- nemocniční lékárny * MeSH
- zdravotní pojištění MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Norsko MeSH
BACKGROUND: Knowledge of co-occurring mental disorders (termed 'dual diagnosis') among patients receiving opioid agonist treatment (OAT) is scarce. This study aimed (1) to estimate the prevalence and structure of dual diagnoses in two national cohorts of OAT patients and (2) to compare mental disorders between OAT patients and the general populations stratified on sex and standardized by age. METHODS: A registry-linkage study of OAT patients from Czechia (N = 4,280) and Norway (N = 11,389) during 2010-2019 was conducted. Data on mental disorders (F00-F99; ICD-10) recorded in nationwide health registers were linked to the individuals registered in OAT. Dual diagnoses were defined as any mental disorder excluding substance use disorders (SUDs, F10-F19; ICD-10). Sex-specific age-standardized morbidity ratios (SMR) were calculated for 2019 to compare OAT patients and the general populations. RESULTS: The prevalence of dual diagnosis was 57.3% for Czechia and 78.3% for Norway. In Czechia, anxiety (31.1%) and personality disorders (25.7%) were the most prevalent, whereas anxiety (33.8%) and depression (20.8%) were the most prevalent in Norway. Large country-specific variations were observed, e.g., in ADHD (0.5% in Czechia, 15.8% in Norway), implying differences in screening and diagnostic practices. The SMR estimates for any mental disorders were 3.1 (females) and 5.1 (males) in Czechia and 5.6 (females) and 8.2 (males) in Norway. OAT females had a significantly higher prevalence of co-occurring mental disorders, whereas SMRs were higher in OAT males. In addition to opioid use disorder (OUD), other substance use disorders (SUDs) were frequently recorded in both countries. CONCLUSIONS: Results indicate an excess of mental health problems in OAT patients compared to the general population of the same sex and age in both countries, requiring appropriate clinical attention. Country-specific differences may stem from variations in diagnostics and care, reporting to registers, OAT provision, or substance use patterns.
- MeSH
- diagnóza dvojí (psychiatrie) MeSH
- dospělí MeSH
- duševní poruchy * epidemiologie farmakoterapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- opiátová substituční terapie * statistika a číselné údaje MeSH
- opioidní analgetika terapeutické užití MeSH
- poruchy osobnosti epidemiologie MeSH
- poruchy spojené s užíváním opiátů * epidemiologie farmakoterapie MeSH
- prevalence MeSH
- registrace * MeSH
- senioři MeSH
- sexuální faktory MeSH
- úzkostné poruchy epidemiologie farmakoterapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Norsko MeSH
Unhealthy aging poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the aging process offers a promising approach to reduce the burden of a number of age-related diseases, such as dementia, and promoting healthy longevity in the old population. In response to the challenge of the aging population and with a view to the future, Norway and the United Kingdom are fostering collaborations, supported by a "Money Follows Cooperation agreement" between the 2 nations. The inaugural Norway-UK joint meeting on aging and dementia gathered leading experts on aging and dementia from the 2 nations to share their latest discoveries in related fields. Since aging is an international challenge, and to foster collaborations, we also invited leading scholars from 11 additional countries to join this event. This report provides a summary of the conference, highlighting recent progress on molecular aging mechanisms, genetic risk factors, DNA damage and repair, mitophagy, autophagy, as well as progress on a series of clinical trials (eg, using NAD+ precursors). The meeting facilitated dialogue among policymakers, administrative leaders, researchers, and clinical experts, aiming to promote international research collaborations and to translate findings into clinical applications and interventions to advance healthy aging.
- MeSH
- demence * prevence a kontrola epidemiologie MeSH
- dlouhověkost MeSH
- lidé MeSH
- senioři MeSH
- stárnutí * MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Norsko MeSH
- Spojené království MeSH
OBJECTIVES: We describe age-specific survival in thyroid cancer (TC) from Denmark, Finland, Norway, and Sweden over a 50-year period. DESIGN: Population-based survival study. METHODS: Relative 5-year survival data were obtained from the NORDCAN database for the years 1972-2021. RESULTS: In the first period 1972-1976, 5-year survival in TC in Finland, Norway, and Sweden was 90% or higher, but a strong negative step-wise age gradient was observed, which was worse for men than women. Over time, survival increased, and in the final period, 2017-2021, survival for all women and Danish men up to age 69 years was about 90% or higher and, for men from the other countries, only marginally lower. Even for older women survival reached 80%, for older men somewhat less. CONCLUSIONS: Age disadvantage in TC survival was for the most part corrected over the 50-year period, and the remaining task is to boost survival for the oldest patients.
- MeSH
- incidence MeSH
- lidé MeSH
- míra přežití MeSH
- nádory štítné žlázy * terapie MeSH
- registrace MeSH
- rizikové faktory MeSH
- senioři MeSH
- věkové rozložení MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Dánsko MeSH
- Finsko MeSH
- Norsko MeSH
- Skandinávie a severské státy MeSH
- Švédsko MeSH
Úvod: Koncept Clubhouse je terapeutická komunita, jejíž členové, včetně těch s duševním onemocněním, stejně jako zaměstnanci, jsou kolegové, kteří bok po boku pracují pro komunitu Clubhouse. Tato kvalitativní studie si klade za cíl prozkoumat zkušenosti členů Clubhouse v Norsku se sociální podporou a využívá salutogenetický přístup. Metody: Do této studie přispělo deset členů Clubhouse v Norsku; šest osob s duševním onemocněním se zúčastnilo polostrukturovaných hloubkových rozhovorů a čtyři pracovníci se zúčastnili pohovoru v cílové skupině. Výsledky: Účastníci vyjádřili tři hlavní témata: (i) společenství podporuje sounáležitost, (ii) zvyšuje víru ve vlastní dovednosti a (iii) vlastní rozhodování podporuje využívání zdrojů. Závěr: Tato studie shrnuje důležitost sounáležitosti, autonomie a participace jako základů zkušenosti se sociální podporou. Budoucí výzkum by se měl zaměřit na členy Clubhouse z menšinového prostředí a na rozdíly ve zkušenostech s výsledky psychosociálního zotavení
Introduction: The Clubhouse concept is a therapeutic community with the philosophy that its members, including those with mental illness as well as the staff, are all colleagues working side by side to perform the work important to the Clubhouse community. This qualitative study aims to explore the experiences that members of a Clubhouse in Norway had with social support and takes a salutogenetic approach. Methods: Ten members of a Clubhouse in Norway contributed to this study; six persons with mental illness participated in semi-structured in-depth interviews and four staff attended a focus group interview. Results: Participants expressed three main themes: (i) a fellowship promotes belonging (ii) increasing belief in one's own skills, and (iii) self-decision-making promotes the use of resources. Conclusion: This study summarises the importance of belonging, autonomy, and participation as the fundamentals of the social support experience. Future research should be focussed on Clubhouse members from minority backgrounds and differences in experiences within psychosocial recovery outcomes.
- MeSH
- duševní poruchy * MeSH
- lidé MeSH
- průzkumy a dotazníky MeSH
- služby v oblasti duševního zdraví komunity MeSH
- sociální opora MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Norsko MeSH
OBJECTIVES: We analyze survival in thyroid cancer from Denmark (DK), Finland (FI), Norway (NO), and Sweden (SE) over a 50-year period (1971-2020), and additionally consider concomitant changes in incidence and mortality. DESIGN: Population-based survival study. METHODS: Relative 1-, 5/1 (conditional)-, and 5-year survival data were obtained from the NORDCAN database for years 1971-2020. Incidence and mortality rates were also assessed. RESULTS: A novel consistent observation was that 1-year survival was worse than 5/1-year survival but the difference between these decreased with time. Relative 1-year survival in thyroid cancer (mean for the 4 countries) reached 92.7% for men and 95.6% for women; 5-year survival reached 88.0% for men and 93.7% for women. Survival increased most for DK which started at a low level and reached the best survival at the end. Male and female incidence rates for thyroid cancer increased 3- and 4-fold, respectively. In the same time, mortality halved for men and for women, it decreased by 2/3. CONCLUSIONS: We documented worse relative survival in the first year than in the 4 subsequent years, most likely because of rare anaplastic cancer. Overall survival in thyroid cancer patients increased in the Nordic countries in the course of 50 years; 5-year survival was close to 90% for men and close to 95% for women. Even though overdiagnosis may explain some of 5-year survival increase, it is unlikely to influence the substantial increase in 1-year survival. The unmet need is to increase 1-year survival by diagnosing and treating aggressive tumors before metastatic spread.
- MeSH
- databáze faktografické MeSH
- lidé MeSH
- nádory štítné žlázy * diagnóza epidemiologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Finsko MeSH
- Norsko MeSH
BACKGROUND: Survival in breast cancer (BC) has developed favorably but late recurrences are still a problem. METHODS: We model survival data from the NORDCAN database and analyze 1-, 5-, and 10-year relative survival and 5/1- and 10/5-year conditional survival in BC from Denmark (DK), Finland (FI), Norway (NO), and Sweden (SE) between 1971 and 2020. Conditional survival measures survival in those who had survived year 1 to reach year 5 (5/1), or in those who had survived year 5 to reach year 10 (10/5). RESULTS: Almost all survival metrics were best for SE but survival in all countries improved in the course of time approaching the SE levels which were 98.3% for 1-year, 92.3% for 5-year, and 87.8% for 10-year survival. Conditional 10/5-year survival, covering 5 years, was better than 5/1-year survival, covering 4 years. A contributing factor is most likely the high rate of recurrence in period 2-5 years. The difference was observed for all countries but for DK 10/5-year survival approached 1-year survival and for NO and SE 10/5-year survival was only barely better than 5/1-year survival. The explanation to this was the excellent 10/5-year survival in DK compared to SE and particularly to NO. Literature search suggested that the reason for the relatively low 10/5-year survival in NO might be stagnant survival development in old patients. CONCLUSIONS: We assume that late mortality is critically limiting survival in BC and either interference with the late metastatic process or effective treatment will be key to future improvements in BC survival.
- MeSH
- lidé MeSH
- míra přežití MeSH
- nádory prsu * epidemiologie terapie MeSH
- registrace MeSH
- rizikové faktory MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Dánsko MeSH
- Finsko MeSH
- Norsko MeSH
- Skandinávie a severské státy MeSH
- Švédsko MeSH
BACKGROUND: Physical diseases represent a significant burden for opioid agonist treatment (OAT) patients. This study described physical morbidity in two national cohorts of OAT patients focusing on gender differences. METHODS: This population-based cohort study linking multiple health registers investigated physical diseases (ICD-10) in patients receiving OAT in the Czech Republic (N = 4,280) and Norway (N = 11,389) during 2010-2019. Gender-stratified analysis was performed. RESULTS: Overall, we found a large burden of physical morbidity across gender groups in OAT patients. In the Czech Republic and Norway, women in OAT had a significantly higher prevalence of physical diseases across most diagnostic chapters, notably genitourinary diseases and neoplasms. Injuries/external causes and infectious/parasitic diseases were among the most common diseases in both women and men. Viral hepatitis accounted for over half of infectious morbidity in women and men in both cohorts. CONCLUSIONS: Our findings support the need for early screening, detection, and treatment of diseases and conditions across organ systems and the integration of health promotion activities to reduce physical morbidity in OAT patients. The gender differences underline the need for a tailored approach to address specific medical conditions.
- MeSH
- kohortové studie MeSH
- lidé MeSH
- opiátová substituční terapie MeSH
- opioidní analgetika * terapeutické užití MeSH
- poruchy spojené s užíváním opiátů * farmakoterapie epidemiologie MeSH
- prevalence MeSH
- sexuální faktory MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Norsko MeSH
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- MeSH
- muži MeSH
- nezaměstnanost MeSH
- vzdělávání odborné - rekvalifikace MeSH
- zdravotničtí pracovníci MeSH
- Geografické názvy
- Norsko MeSH
