Laccases are multi-copper oxidoreductases which catalyze the oxidation of a wide range of substrates during the simultaneous reduction of oxygen to water. These enzymes, originally found in fungi, plants, and other natural sources, have many industrial and biotechnological applications. They are used in the food, textile, pulp, and paper industries, as well as for bioremediation purposes. Although natural hosts can provide relatively high levels of active laccases after production optimization, heterologous expression can bring, moreover, engineered enzymes with desired properties, such as different substrate specificity or improved stability. Hence, diverse hosts suitable for laccase production are reviewed here, while the greatest emphasis is placed on yeasts which are commonly used for industrial production of various proteins. Different approaches to optimize the laccase expression and activity are also discussed in detail here.
- MeSH
- Bacteria genetika MeSH
- hmyz cytologie genetika MeSH
- houby genetika MeSH
- kvasinky genetika MeSH
- lakasa genetika metabolismus MeSH
- proteinové inženýrství metody MeSH
- rekombinantní proteiny genetika metabolismus MeSH
- substrátová specifita MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- MeSH
- Bacteria cytologie genetika MeSH
- biologické hodiny fyziologie genetika MeSH
- chronobiologické jevy * fyziologie genetika MeSH
- cirkadiánní hodiny fyziologie genetika MeSH
- cirkadiánní rytmus - signální peptidy a proteiny fyziologie genetika MeSH
- cirkadiánní rytmus fyziologie genetika MeSH
- eukaryotické buňky cytologie fyziologie MeSH
- financování organizované MeSH
- hmyz cytologie genetika MeSH
- lidé MeSH
- prokaryotické buňky cytologie fyziologie MeSH
- proteiny CLOCK fyziologie genetika MeSH
- savci fyziologie genetika MeSH
- statistika jako téma MeSH
- teoretické modely MeSH
- transkripční faktory ARNTL fyziologie genetika MeSH
- Check Tag
- lidé MeSH