Infections are the emerging causes of mortality and morbidity due to lifelong immunosuppressive therapy in renal transplant patients (1, 4). Here, we report infectious complications of 135 renal allograft recipients who were followed up in the last 20 years in Gülhane Military Medical Academy, Ankara, Turkey. Of them, 83 (61.4%) had a transplant from living related donors, 18 (13.3%) from living non-related HLA matched donors and 34 (25.1%) from cadaveric matched donors. Immunosuppression was achieved in 42 (31.1%) recipients by azathioprine plus corticosteroid (AZA + CS) and in 93 (68.8%) by AZA + CS + cyclosporin A (CsA). Encountered infections were classified according to three different periods of the transplantation procedure [early (first month), intermediate (2-6th months) and late (after the 6th month)]. Bacterial infections were the leading infections in all three periods and the most affected system was the urinary tract. Each recipient had at least one episode of urinary tract infection (UTI) and E. coli was the most common urinary pathogen. On the other hand, HCV was the leading viral pathogen (14.3%). The total mortality rate was 7.4%, and septic shock was the most common cause of death (80%).
- MeSH
- antibiotická profylaxe MeSH
- bakteriální infekce mikrobiologie prevence a kontrola MeSH
- imunosupresivní léčba MeSH
- infekce epidemiologie etiologie MeSH
- lidé MeSH
- mykózy mikrobiologie prevence a kontrola MeSH
- následné studie MeSH
- parazitární nemoci parazitologie prevence a kontrola MeSH
- retrospektivní studie MeSH
- transplantace ledvin škodlivé účinky MeSH
- virové nemoci prevence a kontrola virologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Turecko epidemiologie MeSH
Seroconversion rates of hepatitis B vaccination with increasing antigen doses, in 77 haemodialysis (HD) patients were studied in randomly divided two groups. The first group received the standard 20 microg recombinant HBsAg (rHBsAg) dose, and the second group 40 microg at the 0, 1st and 2nd months of HD. At the end of the study, there were no statistically significant differences between the two groups in the response rates of protective antibody, but the response was always higher in the second group. On the other hand, strong positive antibody response (> or = 100 mlU/ml) according to dates of each dose were as 7.4%, 13.1%, 28.9% and 42.2% in the first group and 50.0%, 50.0%, 60.0% and 52.9% in the second group respectively, and there were statistically significant differences between the two groups in the first three months. We concluded that vaccination with higher antigen doses resulted in a stronger antibody response in the early period in our HD patients. No HBV infection was observed in these two groups in the study period.
- MeSH
- dialýza ledvin * MeSH
- ELISA MeSH
- hepatitida B - antigeny povrchové aplikace a dávkování imunologie MeSH
- hepatitida B - protilátky biosyntéza MeSH
- imunologická odpověď na dávku MeSH
- lidé středního věku MeSH
- lidé MeSH
- prospektivní studie MeSH
- rekombinantní proteiny aplikace a dávkování imunologie MeSH
- vakcína proti hepatitidě B aplikace a dávkování imunologie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky MeSH
- randomizované kontrolované studie MeSH
- Geografické názvy
- Turecko MeSH
- Názvy látek
- hepatitida B - antigeny povrchové MeSH
- hepatitida B - protilátky MeSH
- rekombinantní proteiny MeSH
- vakcína proti hepatitidě B MeSH
Prostitutes are an important group for the transmission of a number of sexually transmitted diseases (STD) all over the world. Infection with T. vaginalis is one of the most common. In this study, the incidence and diagnostic procedures for Trichomonas vaginalis infection as one of the sexually transmitted diseases (STD's) have been studied. In legal prostitutes in Ankara, Turkey, 64 (25%) of 225 vaginal wet smears were positive for T. vaginalis. There was no significant difference between the detection rates of direct phase-contrast microscopy and culture for the identification of T. vaginalis.
- MeSH
- dospělí MeSH
- lidé MeSH
- prevalence MeSH
- prostituce * MeSH
- trichomonádová vaginitida epidemiologie parazitologie MeSH
- Trichomonas vaginalis izolace a purifikace MeSH
- vagina parazitologie MeSH
- zvířata MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Turecko epidemiologie MeSH