Structural changes of thoracic aorta (TA), carotid (CA) and iliac artery (IA) were assessed in Wistar and spontaneously hypertensive rats (SHR) aged 3, 17, and 52 weeks. Systolic blood pressure (sBP) was measured by plethysmography weekly. After perfusion fixation the arteries were processed for electron microscopy. The wall thickness (WT), cross-sectional area (CSA), inner diameter (ID), and WT/ID in all arteries and volume densities of endothelial cells (ECs), muscle cells (SMCs), and extracellular matrix (ECM) in TA were measured and their CSAs were calculated. In 3-week-old SHR compared to Wistar rats, sBP did not differ; in the TA, all parameters (WT, CSA, ID, WT/ID, CSA of SMCs, CSA of ECs, and CSA of ECM) were decreased; in CA, WT and CSA did not differ, ID was decreased, and WT/ID was increased; in IA, WT, CSA, and ID were increased. In 17- and 52-week-old SHRs, sBP and all parameters in all arteries were increased, only ID in IE in 52-week-old SHRs and CSA of ECs in the TA in 17-week-old SHRs did not change. Disproportionality between BP increase and structural alterations during ontogeny in SHR could reflect the flexibility of the arterial tree to the different needs of supplied areas.
- MeSH
- aorta thoracica patologie patofyziologie MeSH
- arteria iliaca patologie patofyziologie MeSH
- arteriae carotides patologie patofyziologie MeSH
- hypertenze patologie patofyziologie MeSH
- krevní tlak fyziologie MeSH
- krysa rodu Rattus MeSH
- potkani inbrední SHR MeSH
- potkani Wistar MeSH
- tunica intima patologie patofyziologie MeSH
- věkové faktory MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
A case report of a patient with unusual compressive syndrome is reported herein. A 27-year-old woman was referred to our hospital due to intermittent claudication in the left thigh and calf which gradually developed over the last five months. Angiography showed an atypical short occlusion of the external iliac artery. Only surgical revision made an exact diagnosis. The formation compressing the artery was a ganglion that originated from the hip joint and adhered to the artery. Resection of the ganglion was carried out. The adjacent segment of the artery was removed and replaced by end-to-end venous graft using vena saphena magna. From the operation until present (30 months) the patient remains symptom-free. To our knowledge a hip joint ganglion compressing the artery and causing symptoms of peripheral arterial disease has not been previously reported in medical literature.
- MeSH
- anastomóza chirurgická MeSH
- angiografie MeSH
- arteria iliaca * patologie chirurgie MeSH
- arteriální okluzní nemoci komplikace etiologie patologie chirurgie MeSH
- cystická ganglia komplikace diagnóza diagnostické zobrazování chirurgie MeSH
- dospělí MeSH
- intermitentní klaudikace etiologie patologie chirurgie MeSH
- kyčelní kloub * MeSH
- lidé MeSH
- tomografie spirální počítačová MeSH
- vena saphena transplantace MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
The aim of this study was to compare the vascular reactivity and morphology of iliac artery (IA) in adult spontaneously hypertensive rats (SHR) and hereditary hypertriglyceridemic (hHTG) rats. The isolated rings of iliac artery (IA) from Wistar rats (controls), SHR and hHTG rats were used for measurement of relaxant responses to acetylcholine (ACh) and contractile responses to noradrenaline (NA). Morphological changes of IA were measured using light microscopy. Systolic blood pressure (BP) measured by plethysmographic method was increased in SHR approximately by 88 % and in hHTG rats by 44 % compared to controls. BP increase was accompanied by cardiac hypertrophy. In both SHR and hHTG groups (experimental groups) reduced relaxation to ACh and enhanced maximal contraction and sensitivity to adrenergic stimuli were observed. The sensitivity to NA in SHR was higher also in comparison with hHTG. Geometry of IA in both experimental groups revealed increased wall thickness and wall cross-sectional area, in SHR even in comparison with hHTG. Inner diameter was decreased in both experimental groups. Thus, independently of etiology, hypertension in both models was connected with impaired endothelial function accompanied by structural alterations of IA. A degree of BP elevation was associated with arterial wall hypertrophy and increased contractile sensitivity.
- MeSH
- acetylcholin farmakologie MeSH
- arteria iliaca účinky léků patologie patofyziologie MeSH
- hypertenze etiologie patologie patofyziologie MeSH
- hypertriglyceridemie patologie patofyziologie MeSH
- krysa rodu Rattus MeSH
- noradrenalin farmakologie MeSH
- potkani inbrední SHR MeSH
- potkani Wistar MeSH
- vazodilatace MeSH
- vazodilatancia farmakologie MeSH
- vazokonstrikce MeSH
- vazokonstriktory farmakologie MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Názvy látek
- acetylcholin MeSH
- noradrenalin MeSH
- vazodilatancia MeSH
- vazokonstriktory MeSH
AIM: To categorize the surgical anatomic variants of the origins of the uterine arteries and to clarify the difference in the description of the internal iliac artery in the contemporary anthropologic, radiologic and surgical system. METHODS: One hundred women with symptomatic fibroids were treated using retroperitoneal laparoscopic dissection of the uterine vessels (LDUV). Retrospective evaluation of the operative records and videos was carried out. The anatomical classification of Adachi (type I-V) was modified for surgical purposes (type I-IV). RESULTS: Laparoscopic retroperitoneal dissection and LDUV were carried out successfully using an ultrasonic operative technique in all women. The branching of the branches of the internal iliac artery was studied on the right side of the pelvis. Of the 100 uterine arteries that were evaluated, 81% were classifiable types and 19% of surgical dissections were inconclusive. Classification was as follows: type I, 30.8%; type II, 23.4%; type III, 45.6%; and type IV was not found. Modified surgical classification type III (visceral branches arising from the umbilical artery and the internal pudendal artery) was claimed to be statistically the most common type. CONCLUSION: Laparoscopic dissection of the uterine artery close to the origin of the uterine artery can be carried out safely in the most frequent types of surgical classification. The meticulous dissection of the uterine artery in cases in which the uterine artery does not arise typically from an unobliterated segment of the internal iliac artery was recommended.
- MeSH
- arteria iliaca patologie MeSH
- arterie patologie chirurgie MeSH
- laparoskopie * MeSH
- leiomyom chirurgie MeSH
- lidé MeSH
- nádory dělohy chirurgie MeSH
- ultrasonografie MeSH
- uterus krevní zásobení MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Four cases of infected vascular prosthetic graft in the groin successfully treated with povidone-iodine solution using a conservative approach are described here. In all patients the same technique was used. After complete debridement, the prosthetic graft in the groin was completely exposed. The wound was cleansed with hydrogen peroxide and then dressed with gauze soaked in 1:10 sterile water-diluted povidone-iodine solution. The dressings were changed twice a day. The patients were supplemented by systemic therapy of an appropriate antibiotic. All patients were observed in the intensive care unit. In all patients this treatment method led to control of infection and healing of the wound. Thus, it was not necessary to remove the prosthetic graft and patients were spared a major surgical intervention. At follow-up, the prosthetic grafts remain patent without any signs of recurrence of infection.
- MeSH
- antiinfekční látky lokální terapeutické užití MeSH
- arteria femoralis patologie chirurgie MeSH
- arteria iliaca patologie chirurgie MeSH
- arteria poplitea patologie chirurgie MeSH
- arteriální okluzní nemoci chirurgie MeSH
- cévní protézy škodlivé účinky MeSH
- dolní končetina krevní zásobení chirurgie MeSH
- enterobakteriální infekce etiologie terapie MeSH
- infekce spojené s protézou etiologie terapie MeSH
- jodovaný povidon terapeutické užití MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- streptokokové infekce etiologie terapie MeSH
- třísla chirurgie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- antiinfekční látky lokální MeSH
- jodovaný povidon MeSH
Using the electron microscope, the authors examined the structure of the wall in a case of arteriomegaly of the inferior mesenteric artery in man. Structural changes concerned the elastic material showing signs of degeneration. Based on a comparison with literary findings, the authors conclude that tortuosity of the arteries, aneurysms and arteriomegaly are caused by congenital, age-dependent and pathological changes in the elastic material in the vessel wall. There exist basic structural differences in the arterial wall in arteriomegaly and in atherosclerosis.
- MeSH
- aneurysma břišní aorty patologie MeSH
- aneurysma patologie MeSH
- arteria iliaca patologie MeSH
- arteriae mesentericae patologie MeSH
- dilatace patologická patologie MeSH
- elastická tkáň patologie MeSH
- kolagen metabolismus MeSH
- lidé MeSH
- senioři MeSH
- svaly hladké cévní patologie MeSH
- tunica intima patologie MeSH
- tunica media patologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- kolagen MeSH
