Circulating tumor cells (CTCs), detached from the primary tumor or metastases and shed in the patient's bloodstream, represent a relatively easily obtainable sample of the cancer tissue that can indicate the actual state of cancer, and their evaluation can be repeated many times during the course of treatment. As part of liquid biopsy, evaluation of CTCs provides a lot of clinically relevant information, which reflects the actual, real-time conditions of the disease. CTCs can be used in cancer diagnosis or screening, real-time long-term disease monitoring and even therapy guidance. Their analysis can include their number, morphology, and biological features by using immunocytochemistry and all "-omic" technologies. This review describes methods of CTC isolation and potential clinical utilization in lung cancer.

• Klíčová slova
• Circulating tumor cells, biomarker, culturing, liquid biopsy, lung cancer, review,
• MeSH
• časná detekce nádoru MeSH
• diagnostické techniky molekulární MeSH
• lidé MeSH
• nádorové biomarkery MeSH
• nádorové cirkulující buňky metabolismus   patologie   MeSH
• nádory plic diagnóza   etiologie   terapie   MeSH
• tekutá biopsie metody   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Názvy látek
• nádorové biomarkery MeSH