The main topic of this study is a human health risk assessment of a defined exposure scenario in the floodplain soils of the headwater areas of the central European watershed, with the aim of exploring both multivariate and regional data structures. Flood-prone areas are recognized worldwide to be susceptible to contamination and its redistribution. Contributions of various classes of toxic compounds (organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs)) to human health risks were assessed in a screening risk assessment. However, due to the relative nature of our data and a high PAH dominancy over the data ensemble, reliance solely on the standard statistical processing of raw data might lead to incomplete insight into the structure of the multivariate data. Explanatory analysis of the data structure using the compositional approach was found to be beneficial to elucidating human health risk profiles and provided robust evidence that a contrast between agricultural and airborne industrial pollution controlled the whole human toxicological variation of persistent organic pollutants (POPs) in floodplain soils. These results were effectively quantified with the subcomposition of benzo(a)pyrene, DDT, and alpha-hexachlorocyclohexane (aHCH), allowing for an interpretation of structural differences in regional pollution patterns, which conferred different extents and compositions of human health risks in floodplain soils.

• Klíčová slova
• compositional data, floodplain, human health risk, soil pollution,
• MeSH
• algoritmy MeSH
• chlorované uhlovodíky analýza   MeSH
• hexachlorcyklohexan analýza   MeSH
• látky znečišťující půdu analýza   MeSH
• látky znečišťující životní prostředí analýza   MeSH
• lidé MeSH
• monitorování životního prostředí * MeSH
• pesticidy analýza   MeSH
• polychlorované bifenyly analýza   MeSH
• polycyklické aromatické uhlovodíky analýza   MeSH
• půda chemie   MeSH
• záplavy * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Evropa MeSH
• Názvy látek
• alpha-hexachlorocyclohexane MeSH Prohlížeč
• chlorované uhlovodíky MeSH
• hexachlorcyklohexan MeSH
• látky znečišťující půdu MeSH
• látky znečišťující životní prostředí MeSH
• pesticidy MeSH
• polychlorované bifenyly MeSH
• polycyklické aromatické uhlovodíky MeSH
• půda MeSH

To assess the long-term anthropogenic load of the Bílina River (Czech Republic), the concentrations of heavy metals and specific organic compounds in different river ecosystem matrices (water, biofilms, and sediments) were determined. Although the current concentrations of pollutants in surface water are low, frequently below the limits of the quantitative analytical methods used, the river ecosystem is still heavily loaded by anthropogenic pollution, mainly from the chemical and mining industries. This was demonstrated by analyzing biofilms and sediments. These matrices are more accurate representatives of the actual situation in the river and do not depend on hydrological conditions or random variability in water quality. The results indicate that the middle and the lower parts of the river are heavily polluted by mercury, arsenic, vanadium, polychlorinated biphenyls, hexachlorobenzene, and dichloro-diphenyl-trichloroethane. As a tributary of the Elbe River, the Bílina River represents a significant risk for the development of quality in this major European river.

• MeSH
• biofilmy * MeSH
• chemické látky znečišťující vodu analýza   MeSH
• geologické sedimenty chemie   MeSH
• organické látky analýza   MeSH
• sběr dat MeSH
• sladká voda chemie   MeSH
• těžké kovy analýza   MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Česká republika MeSH
• Názvy látek
• chemické látky znečišťující vodu MeSH
• organické látky MeSH
• těžké kovy MeSH

Biochemical markers, specifically enzymes of the first phase of xenobiotic transformation - cytochrome P450 and ethoxyresorufin-O-deethylase (EROD) - were used to determine the quantities of persistent organic pollutants (POPs) in fish muscle (PCB, HCB, HCH, OCS, DDT). Eight rivers were monitored (Orlice, Chrudimka, Cidlina, Jizera, Vltava, Ohře and Bílina; and the River Blanice was used as a control). The indicator species selected was the chub (Leuciscus cephalus L.). There were no significant differences in cytochrome P450 content between the locations monitored. The highest concentration of cytochrome P450 in fish liver was in the Vltava (0.241 nmol mg-1 protein), and the lowest was in the Orlice (0.120 nmol mg-1 protein). Analysis of EROD activity showed a significant difference between the Blanice and the Vltava (P< 0.05), and also between the Orlice and the Vltava (P< 0.01), the Orlice and the Bílina (P< 0.01), and the Orlice and the Ohře (P< 0.05). The highest EROD activity in fish liver was in the Vltava (576.4 pmol min-1 mg-1 protein), and the lowest was in the Orlice (63.05 pmol min-1 mg-1 protein). In individual locations, results of chemical monitoring and values of biochemical markers were compared. A significant correlation (P< 0.05) was found between biochemical markers and OCS, and PCB. Among the tributaries studied those that contaminated the Elbe most were the Vltava and the Bílina. These tributaries should not be considered the main sources of industrial contamination of the River Elbe, because the most important contamination sources were along the river Elbe itself.

• Klíčová slova
• EROD, Leuciscus cephalus L., River Elbe, cytochrome P450, persistent organic pollutants,
• Publikační typ
• časopisecké články MeSH