Nejvíce citovaný článek - PubMed ID 18080453
PURPOSE OF REVIEW: Cancer diagnosis in young pregnant women challenges oncological decision-making. The International Network on Cancer, Infertility and Pregnancy (INCIP) aims to build on clinical recommendations based on worldwide collaborative research. RECENT FINDINGS: A pregnancy may complicate diagnostic and therapeutic oncological options, as the unborn child must be protected from potentially hazardous exposures. Pregnant patients should as much as possible be treated as non-pregnant patients, in order to preserve maternal prognosis. Some approaches need adaptations when compared with standard treatment for fetal reasons. Depending on the gestational age, surgery, radiotherapy, and chemotherapy are possible during pregnancy. A multidisciplinary approach is the best guarantee for experience-driven decisions. A setting with a high-risk obstetrical unit is strongly advised to safeguard fetal growth and health. Research wise, the INCIP invests in clinical follow-up of children, as cardiac function, neurodevelopment, cancer occurrence, and fertility theoretically may be affected. Furthermore, parental psychological coping strategies, (epi)genetic alterations, and pathophysiological placental changes secondary to cancer (treatment) are topics of ongoing research. Further international research is needed to provide patients diagnosed with cancer during pregnancy with the best individualized management plan to optimize obstetrical and oncological care.
- Klíčová slova
- Cancer, Fertility, INCIP, Pregnancy, Research,
- MeSH
- adaptace psychologická MeSH
- internacionalita MeSH
- lidé MeSH
- nádorové komplikace v těhotenství * diagnóza epidemiologie psychologie terapie MeSH
- nádory diagnóza epidemiologie psychologie terapie MeSH
- nemoci placenty diagnóza etiologie terapie MeSH
- novorozenec MeSH
- registrace statistika a číselné údaje MeSH
- těhotenství MeSH
- týmová péče o pacienty MeSH
- výsledek těhotenství epidemiologie MeSH
- ženská infertilita epidemiologie prevence a kontrola MeSH
- Check Tag
- lidé MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH