Sera of 112 healthy Hungarian blood donors were tested for the presence of Yersinia enterocolitica and Y. pseudotuberculosis-specific agglutinins by tube agglutination, and for that of yersinia outer membrane protein (Yop)-specific IgA antibodies by ELISA. The positive results of this latter assay were confirmed by immunoblot. Only one sample gave a positive agglutination reaction with Y. enterocolitica antigen (group 03) and four exhibited an equivocal reaction with Y. pseudotuberculosis antigens (groups II and IV). Contrary to the low incidence of agglutinins, 15.1% of the samples showed a positive Yop-specific IgA reaction, while further 5.3% samples fell into the equivocal range by ELISA (17 and 6 specimens, respectively). Eleven of these samples (9.8% of all specimens tested) were also positive by immunoblot for the presence of Yop-specific IgA antibodies. These data suggest a higher incidence of yersinia infections than the 1.0-1.4 per 10(5) population predicted on the basis of stool culture results.

• MeSH
• Agglutination Tests MeSH
• Blood Donors * MeSH
• Adult MeSH
• Enzyme-Linked Immunosorbent Assay MeSH
• Immunoblotting MeSH
• Immunoglobulin A blood   MeSH
• Yersinia Infections epidemiology   immunology   MeSH
• Middle Aged MeSH
• Humans MeSH
• Bacterial Outer Membrane Proteins immunology   MeSH
• Antibodies, Bacterial blood   MeSH
• Antibody Specificity MeSH
• Yersinia enterocolitica immunology   MeSH
• Yersinia pseudotuberculosis immunology   MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Hungary epidemiology   MeSH
• Names of Substances
• Immunoglobulin A MeSH
• Bacterial Outer Membrane Proteins MeSH
• Antibodies, Bacterial MeSH