Kazuistiky
Dotaz
Zobrazit nápovědu
Hepatoblastoma is an uncommon malignant neoplasm in general, yet, it is the most common liver malignancy in children with the incidence about one per milion children. This type of liver tumor usually occurs before the age of three years. The etiology of hepatoblastoma remains unknown. However, there are some genetic conditions known to be associated with an increased risk of developing hepatoblastoma such as Beckwith-Wiedemann syndrome, hemihypertrophy, APC-associated polyposis, α-1-antitrypsin defficiency and some metabolic disorders including tyrosinemia, galactosemia and glycogen storage disease type 1. There is a higher risk of hepatoblastoma in children with very low birthweight, children who acquire hepatitis B at an early age and children with congenital biliary atresia.
- MeSH
- Beckwithův-Wiedemannův syndrom komplikace MeSH
- dítě MeSH
- galaktosemie komplikace MeSH
- glykogenóza typu I komplikace MeSH
- hepatitida B komplikace MeSH
- hepatoblastom etiologie genetika MeSH
- lidé MeSH
- nádory jater etiologie genetika MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- práce podpořená grantem MeSH
Lymphangioleiomyomatosis (LAM) is a rare progressive disease affecting women of childbearing age. The disease is characterised by an abnormal proliferation of immature smooth muscle cells predominantly in the lung. It gradually leads to respiratory failure, and it frequently result in death. Extrapulmonary LAM typically presents with abdominal mass, abdominal pain and chylous ascites. In the case reports we describe two cases of premenopausal females with extrapulmonary LAM. In both cases they occur in pelvic location in the obturator fossa and around the external iliac artery. After surgical procedures patients were primary treated with progesterone. Sirolimus was second-line drugs.
- MeSH
- dospělí MeSH
- lidé MeSH
- lymfangioleiomyomatóza * MeSH
- progesteron terapeutické užití MeSH
- protinádorové látky terapeutické užití MeSH
- retroperitoneální nádory * MeSH
- sirolimus terapeutické užití MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- progesteron MeSH
- protinádorové látky MeSH
- sirolimus MeSH
Furuncular myiasis caused by the larvae of the human botfly, Dermatobia hominis, is a common disease in tropical areas of Latin America and may therefore occur in travelers returning from that region. Outside the endemic areas, the diagnosis is often delayed because the disease is mistaken for a bacterial skin infection. Reported are two cases of furuncular myiasis in patients returning from Central and South America.
Two cases of imported visceral leishmaniasis are described. The first patient was a 32-year-old Czech man who developed leishmaniasis 5 months after a holiday in Italy (Bibione). The second patient was a 62-year-old Czech man who developed leishmaniasis 18 months after visiting Croatia (Makarska); the disease began after a course of chemotherapy due to metastasizing testicular tumor. Both patients were successfully treated with amphotericin B lipid complex (Abelcet). Difficulties in establishing the correct diagnosis of visceral leishmaniasis are discussed.
- MeSH
- cestování MeSH
- dospělí MeSH
- imunokompromitovaný pacient MeSH
- leishmanióza viscerální diagnóza farmakoterapie imunologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
Morbid obesity (BMI over 40 kg/m2) is typically complicated by many serious diseases including early death. Using 7 case studies of morbid obese patients we are documenting severe polymorbidity of these persons including severe manifestation of metabolic syndrome. Using adequate therapy, e.g. gastric banding, risk of these patients can be reduced. Some parts of metabolic syndrome can be documented in adolescent children of these patients. The aim of this study is to show the importance of early intervention in patients with morbid obesity.
- MeSH
- dospělí MeSH
- lidé MeSH
- morbidní obezita * komplikace terapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
Cystic retrorectal tumors are rare tumors with a risk potential for a malignant growth. Their diagnostics, location and decision on the surgical approach--abdominal, perineal or combined--are based on ultrasound, CT and MRI examination findings. A complete removal of the neoplasm without opening the wall of the cystic tumor is a pre-requisite for a good therapeutical result.
- MeSH
- cysty diagnóza patologie chirurgie MeSH
- dermoidní cysta diagnóza patologie chirurgie MeSH
- dospělí MeSH
- lidé MeSH
- nádorové komplikace v těhotenství diagnóza patologie chirurgie MeSH
- nádory pánve diagnóza patologie chirurgie MeSH
- nádory rekta diagnóza patologie chirurgie MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
OBJECTIVE: Analysis of two cases uterine rupture following caesarian section. SUBJECT: Two case studies. SETTING: Gynecological obstetrics clinic, First Medical Faculty and Faculty Hospital Bulovka, Prague. SUBJECT AND METHODS: The authors in their article describe two cases of rupture of the uterus in pregnancy prior to delivery. In both cases there was a history of cervicocorporal caesarian section. CONCLUSION: In the first case the patient was admitted from her home with bleeding, and signed a nonconsent form. The second case concerned a hospitalized patient, in which the first signs of uterine rupture were indicated by fetal heart rate. Both women underwent hysterectomy, paradoxically, in the first case the child was saved and discharged home in good health.
- MeSH
- císařský řez škodlivé účinky MeSH
- dospělí MeSH
- komplikace porodu diagnóza etiologie chirurgie MeSH
- lidé MeSH
- ruptura dělohy diagnóza etiologie chirurgie MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
The authors describe the case-histories of three pregnant patients with acute appendicitis treated laparoscopically. They present a brief account of laparoscopic appendectomy in pregnant women and demonstrate on the described cases its advantages and safety.
- MeSH
- akutní nemoc MeSH
- apendektomie * metody MeSH
- apendicitida chirurgie MeSH
- dospělí MeSH
- komplikace těhotenství chirurgie MeSH
- laparoskopie * MeSH
- lidé MeSH
- těhotenství MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
Small, usually supernumerary chromosomes, denoted as marker chromosomes or markers, can be represented by various phenotypic expression, that depends on their origin and extent. Our article presents results of molecular cytogenetic analysis (FISH) of 34 patients with identified marker chromosome. In 21 cases a marker derived from acrocentric chromosome was identified, in 9 cases markers of gonosomal origin [der(X), der(Y)], and in 4 patients markers of some other chromosomes (5, 17, 18) were proved. The most frequent marker was that originating from chromosome 15 (8 cases). Two patients with different phenotype, markedly influenced by the extent of pseudoizodicentric chromosome 15 are described. In accordance with hitherto presented data, presence of supernumerary copies of the critical region PWACR (it is the partial trisomy, resp. tetrasomy 15q11-q13) in majority of cases brings about serious affection described as syndrome of the inverted duplication of chromosome 15. The most typical symptoms are psychomotoric retardation, hypotony, neurological symptoms and autistic features. The article stresses the importance of FISH method in the prenatal examination of marker chromosomes.
- MeSH
- chromozomální aberace * MeSH
- dospělí MeSH
- fenotyp MeSH
- hybridizace in situ fluorescenční * MeSH
- karyotypizace MeSH
- kojenec MeSH
- lidé MeSH
- novorozenec MeSH
- Check Tag
- dospělí MeSH
- kojenec MeSH
- lidé MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
OBJECTIVE: The authors demonstrate two cases of caudal regression syndrome (CRS), a rare malformative syndrom, seen mainly in cases of maternal diabetes with poor metabolic control. DESIGN: Case report. SETTING: Department of Obstetrics and Gynecology, Department of Medicine Regional Hospital Pardubice. CASES: The caudal regression syndrome (CRS) was revealed in two women with praegestational diabetes. The diagnosis was made at 18 and 20 weeks. The characteristic ultrasound findings include abrupt interruption of the spine and abnormal position of the lower limbs. The femur bones are fixed in a "V" pattern, giving a typical "Buddha's poise". A complete examination must be conducted for possible urinary and intestinal malformations. The mechanism leading to malformation is discussed in the article. To prevent pregnancy at the time of bad controlled diabetes is the only way to minimaze the risk of producing a congenitally malformed baby including caudal regression syndrom in the population of diabetic mothers. Family planning and supervision by the specialists is always advisable. CONCLUSION: Early diagnosis of CRS is possible using vaginal ultrasound. Emphasis is placed on the association of abrupt disruption of dorsal or lumbar spine and abnormal images of the lower limbs fixed in a,,V" formation, which is characteristic sign of CRS.
- MeSH
- dospělí MeSH
- lidé MeSH
- lumbosakrální krajina abnormality MeSH
- mnohočetné abnormality diagnostické zobrazování etiologie patologie MeSH
- novorozenec MeSH
- potrat eugenický MeSH
- syndrom MeSH
- těhotenství při diabetu * MeSH
- těhotenství MeSH
- ultrasonografie prenatální MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- novorozenec MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
