Objective criteria Dotaz Zobrazit nápovědu
Renewable energies are interesting as an alternative and sustainable resource for air conditioning applications. But initial investment cost of equipment, whose employed for converting the renewable energy into usable shape and also for air conditioning duty, are significant. Therefore, determining the optimum sizing has high priority. In current study, water cooled vapor compression refrigeration cycle powered by wind energy and storage tank is proposed, simulated and optimized. To contribute the total effective aspects in system optimum size, the thermo-economic-environmental criteria is defined. By the help of databank of parametric analysis, the optimum design variables are determined by employing the GA optimization algorithm. In the following, an intelligence neural network is developed to learn the reliable correlation between the inputs and outputs data. Finally, the optimum size of each subsystem is determined by using triple-objective MPSO. Based on detailed economic analysis, the system payback period is estimated about 450 days which is 41% less than the conventional system. The daily COP and exergy efficiency of the whole system has improved up to 98% and 40%, after substituting the optimum design variable parameters. Triple-objective MPSO results show that, the ice storage tank should be selected 22% smaller than the initial amount.
- Klíčová slova
- 5E analysis, Cold storage, Compression cycle, Triple-objective MPSO optimization, Wind energy,
- Publikační typ
- časopisecké články MeSH
The halal meat industry is today a reality in many regions of the world, including the European Union. The main religious laws in the area of halal meat production were legislated in ancient times and may be unchangeable due to their sanctity perceived by faithful Muslims, while the modern technology used in the meat industry is constantly evolving and being updated. The objective of this study is to highlight the points of controversy between the principles of halal and the technological means currently used in the meat industry. Modern slaughter practices, including animal fasting prior to slaughter, animal body position, the location of the incision during slaughter, stunning and mechanical slaughter, are reviewed. The purpose of preslaughter feed availability according to halal criteria could be to ensure greater welfare for animals, though feed withdrawal is necessary today. Although there is no clear unified opinion among the Islamic sects, reversible stunning of animals is generally accepted. A neck cut at a higher position than the conventional low cut in cattle may reduce the compromise in welfare (the onset of unconsciousness), minimise false aneurysm and be compatible with halal criteria. This study may contribute towards consideration being given to technology that is not in conflict with the religious legislation, while at the same time meeting the requirements of the modern meat industry.
- Klíčová slova
- animal welfare, halal criteria, slaughter, stunning,
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
OBJECTIVE: Provide background to the debate on the criteria for selecting a surrogate mother, if the procedure should be regulated in the Czech Republic. DESIGN: Qualitative content analysis of documents. SETTING: Faculty of Health and Social Studies, University of South Bohemia, České Budějovice; AK Prudil et al., Brno. METHODS: Several sources of data have been used: 1. Legal documents of several European countries where surrogate motherhood is regulated by law: UK, NL, Greece, Portugal. 2. The websites of agencies that mediate surrogate motherhood; analysed number: 23. RESULTS: The most frequently mentioned criterion for selection a surrogate mother was her parental status and gynecological history. Further, the requirements related to age, state of health (exclusion of psychiatric diagnosis), lifestyle. Less often, BMI requirements, citizenship, relationship with the applicant, marital status, impeccability, financial stability, number of procedures underwent. In addition, difficult-to-assess features, such as willingness to process or family support, are required. CONCLUSION: The criteria formulated by the SAR ČGPS ČLS are highly qualified, taking into account the complexity of the procedure. We recommend to reconsider the upper age limit and the number of procedures that an adept can pass (we recommend one). The psychologist should be qualified in psychodiagnostics. We recommend starting negotiations with professional psychological societies about his required qualifications. We also recommend accepting this procedure only for couples residing in the Czech Republic.
- Klíčová slova
- assisted reproduction, criteria, surrogate mother,
- MeSH
- kvalitativní výzkum MeSH
- lidé MeSH
- náhradní matky * MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
- Evropa MeSH
BACKGROUND AND AIM: The otolaryngologist often meets with fractures of the orbital floor. The most serious complication is diplopia, arising as a result of herniation of the orbital contents, with or without fixation of the inferior rectus muscle. The aim of our work was to create a mathematical model to calculate the volume of prolapsed soft tissue of the orbit in blow-out fractures, as a factor in deciding on the need for surgical treatment. PATIENTS AND METHODS: In a retrospective study (2007-2013), we evaluated 80 patients with blow-out fractures, divided into two equal groups: 40 conservatively treated and 40 surgically treated patients. We created the model by measuring the fracture lines and herniation of the orbital soft tissues in the coronal and sagittal sections from CT images, equivalent to half the volume of a rotating ellipsoid. RESULTS: According to the proposed model, posterior and anterior fractures with a prolapse volume above 500 mm3, and anteroposterior fractures with a volume over 1400 mm3, are indicated for surgery. CONCLUSION: The volume of prolapsed soft tissue relative to the location of the fracture is the main indicator for selecting the best treatment procedure immediately after injury.
- Klíčová slova
- CT-assisted surgery, blow-out fractures, diplopia, volumometry,
- MeSH
- dospělí MeSH
- fraktury očnice komplikace chirurgie terapie MeSH
- hernie diagnostické zobrazování etiologie MeSH
- konzervativní terapie * MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- počítačová rentgenová tomografie MeSH
- prolaps MeSH
- retrospektivní studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- teoretické modely * MeSH
- výběr pacientů MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: As a part of regular revision of the List of Occupational Diseases in the Czech Republic, efforts have been made to add a new item so that lumbar spine disease caused by overload may be recognized as occupational one, with adherence to the valid national rules, that is, clinical criteria are met and objective assessment confirms working conditions under which, according to recent scientific knowledge, such an occupational disease develops. The aim is to provide information on the use of a proposed method for working condition assessment in a real setting, based on the initial experiences gained from a pilot study carried out to validate the method. METHODS: Working conditions were assessed in 55 individuals with chronic low back pain (25 males, 30 females; mean age 45.6 years; mean length of employment 15.6 years). The assessment was based on estimating compressive force on the L4/L5 intervertebral disc when performing potentially high-risk work tasks which were entered into four types of checklists throughout their work shifts. The compression values were calculated using a special module that was developed. RESULTS: In 24 cases comprehensive assessment of all tasks performed showed fulfillment of the proposed criteria of working conditions needed for recognition of occupational disease. Those included healthcare, foundry and forest workers, production operators, cabinetmakers, locksmiths, bricklayers, etc. In all the cases, lumbar spine overload was associated with work tasks requiring combinations of manual handling of objects and trunk rotation or bending. The criteria were not met in 31 subjects. The mean length of employment was 15.4 and 15.8 years in patients who met and did not meet the proposed criteria, respectively. CONCLUSION: The proposed method proved to be applicable in occupational hygiene evaluation in a real setting.
- Klíčová slova
- checklists, chronic lumbar spine diseases, lumbar spine overload, occupational hygiene criteria, occupational risk factors,
- MeSH
- bederní obratle patofyziologie MeSH
- biomechanika fyziologie MeSH
- chronická bolest patofyziologie MeSH
- kontrolní seznam MeSH
- lidé středního věku MeSH
- lidé MeSH
- lumbalgie patofyziologie MeSH
- nemoci z povolání patofyziologie MeSH
- plnění a analýza úkolů MeSH
- zaměstnání MeSH
- zatížení muskuloskeletálního systému fyziologie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
BACKGROUND: Targets for right-sided conduction system pacing (CSP) include His bundle and right bundle branch. Electrocardiographic patterns, diagnostic criteria, and outcomes of right bundle branch pacing (RBBP) are not known. OBJECTIVE: Our aims were to delineate electrocardiographic and electrophysiological characteristics of RBBP and to compare outcomes between RBBP and His bundle pacing (HBP). METHODS: Patients with confirmed right CSP were divided according to the conduction system potential to QRS complex interval at the pacing lead implantation site. Six hypothesized RBBP criteria as well as pacing parameters, echocardiographic outcomes, and all-cause mortality were analyzed. RESULTS: All analyzed criteria discriminated between HBP and RBBP: double QRS complex transition during the threshold test, selective paced QRS complex different from conducted QRS complex, stimulus to selective-QRS complex > potential-QRS complex, small increase in V6 R-wave peak time (V6RWPT) during QRS complex transition, equal capture thresholds of CSP and myocardium, and stimulus-V6RWPT > potential-V6RWPT (adopted as the diagnostic standard). According to the last criterion, RBBP was observed in 19.2% of patients (64 of 326) who had been targeted for HBP, present mainly among patients with potential to QRS complex interval <35 ms (90.6% [48 of 53]) and occasionally among the remaining patients (5.6% [16 of 273]). RBBP was characterized by longer QRS complex (by 10.5 ms), longer V6RWPT (by 11.6 ms), and better sensing (by 2.6 mV) compared with HBP. During a median follow-up duration of 29 months, no differences in capture threshold, echocardiographic outcomes, or mortality were found. CONCLUSION: RBBP has distinct features that separate it from HBP and is observed in approximately a fifth of patients in whom HBP is intended.
- Klíčová slova
- Capture criteria, Conduction system pacing, ECG, His bundle pacing, Right bundle branch pacing,
- MeSH
- echokardiografie MeSH
- elektrokardiografie MeSH
- Hisův svazek MeSH
- kardiostimulace umělá * MeSH
- lidé MeSH
- nemoci převodního systému srdečního MeSH
- převodní systém srdeční * MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Various explicit screening tools, developed mostly in central Europe and the USA, assist clinicians in optimizing medication use for older adults. The Turkish Inappropriate Medication use in oldEr adults (TIME) criteria set, primarily based on the STOPP/START criteria set, is a current explicit tool originally developed for Eastern Europe and subsequently validated for broader use in Central European settings. Reviewed every three months to align with the latest scientific literature, it is one of the most up-to-date tools available. The tool is accessible via a free mobile app and website platforms, ensuring convenience for clinicians and timely integration of updates as needed. Healthcare providers often prefer to use their native language in medical practice, highlighting the need for prescribing tools to be translated and adapted into multiple languages to promote optimal medication practices. OBJECTIVE: To describe the protocol for cross-cultural and language validation of the TIME criteria in various commonly used languages and to outline its protocol for clinical validation across different healthcare settings. METHODS: The TIME International Study Group comprised 24 geriatric pharmacotherapy experts from 12 countries. In selecting the framework for the study, we reviewed the steps and outcomes from previous research on cross-cultural adaptations and clinical validations of explicit tools. Assessment tools were selected based on both their validity in accurately addressing the relevant issues and their feasibility for practical implementation. The drafted methodology paper was circulated among the study group members for feedback and revisions leading to a final consensus. RESULTS: The research methodology consists of two phases. Cross-cultural adaptation/language validation phase follows the 8-step approach recommended by World Health Organization. This phase allows regions or countries to make modifications to existing criteria or introduce new adjustments based on local prescribing practices and available medications, as long as these adjustments are supported by current scientific evidence. The second phase involves the clinical validation, where participants will be randomized into two groups. The control group will receive standard care, while the intervention group will have their treatment evaluated by clinicians who will review the TIME criteria and consider its recommendations. A variety of patient outcomes (i.e., number of hospital admissions, quality of life, number of regular medications [including over the counter medications], geriatric syndromes and mortality) in different healthcare settings will be investigated. CONCLUSION: The outputs of this methodological report are expected to promote broader adoption of the TIME criteria. Studies building on this work are anticipated to enhance the identification and management of inappropriate medication use and contribute to improved patient outcomes.
OBJECTIVE: The aim of this study was to determine the prevalence of potentially inappropriate medications (PIMs) in nursing home residents across eight countries and investigate differences between residents with and without cognitive impairment, as well as those with and without life expectancy of six months or less. METHODS AND DEIGN: The study utilized the second edition of the STOPP-Frail criteria to operationalize PIMs in the baseline assessment of nursing home residents participating in the Services and Health for Elderly in Long TERm care (SHELTER) project. The data were collected between 2009 and 2012. The project was conducted in eight countries: Czech Republic, England, Finland, France, Germany, Italy, the Netherlands, and Israel. Cognitive impairment was measured by the cognitive performance scale (CPS). The presence of end-stage disease with a life expectancy of six months or less was recorded. The study included residents aged 60 years or older who underwent a valid medication assessment. RESULTS: Among the 3,832 eligible residents, 87.9% had at least one PIM. Specifically, 24.3%, 23.5%, 18.8%, and 19.3% of residents had one, two, three, and four or more PIMs, respectively. On average, each person was prescribed 2.16 PIMs. Cognitively impaired residents (n = 1999) had an average of 1.96 PIMs (SD 1.49) per person, while residents with a low CPS score (n = 1783) had an average of 2.40 PIMs (SD 1.57) per person, showing a statistically significant difference (P < 0.001). Similarly, NH residents with life expectancy of six months or less had an average of 1.66 PIMs (SD 1.30), whereas those without had an average of 2.17 PIMs (SD 1.55) (p < 0.001). The average number of PIMs varied across countries, ranging from 3.23 in Finland to 2.15 in the UK (P < 0.001). Anti-platelets and aspirin were the most prescribed PIMs, accounting for over 38.0% of prescriptions. CONCLUSIONS: This study highlights the high prevalence of PIMs among nursing home residents. However, PIMs were somewhat lower in residents with cognitive impairment and life expectancy of six months or less. Efforts must continue to improve the rationale behind prescribing practices in nursing homes.
- Klíčová slova
- Adverse effects, Cognitive impairment, End-of-life, Nursing home residents, Potentially inappropriate medications,
- MeSH
- domovy pro seniory MeSH
- křehký senior MeSH
- lidé středního věku MeSH
- lidé MeSH
- nevhodné předepisování statistika a číselné údaje MeSH
- pečovatelské domovy * MeSH
- prevalence MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- seznam potenciálně nevhodných léčiv * MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- Geografické názvy
- Německo epidemiologie MeSH
BACKGROUND: During left bundle branch (LBB) area pacing, it is important to confirm that capture of the LBB, and not just capture of only adjacent left ventricular (LV) myocardium, has been achieved. OBJECTIVE: The purpose of this study was to establish electrocardiographic (ECG) criteria for LBB capture. We hypothesized that because LBB pacing results in physiological depolarization of the LV, then the native QRS can serve as a reference for diagnosis of LBB capture in the same patient. METHODS: Only patients with evidence of LBB capture (QRS morphology transition) were included. Several QRS characteristics were compared between the native rhythm and different types of LBB area capture. RESULTS: A total of 357 ECGs (124 patients) were analyzed: 118 with native rhythm, 124 with nonselective LBB capture, 69 with selective LBB capture, and 46 with LV septal capture. Our hypotheses that during LBB capture the paced V6 R-wave peak time (RWPT; measured from QRS onset) equals the native V6 RWPT and that the paced V6 RWPT (measured from the stimulus) equals the LBB potential to V6 R-wave peak interval were positively validated. Criteria based on these rules had sensitivity and specificity of 88.2%-98.0% and 85.7%-95.4%, respectively. Moreover, 100% specific V6 RWPT cutoff for LBB capture diagnosis in patients with narrow QRS/right bundle branch block was determined to be 74 ms. CONCLUSION: We showed equivalency of LV activation times on ECG during native and paced LBB conduction. Therefore, if V6 RWPT is longer during pacing, this finding is indicative of lack of LBB capture.
- Klíčová slova
- Electrocardiographic criteria, Left bundle branch pacing, Left ventricular activation time, Physiological pacing, R-wave peak time,
- MeSH
- blokáda Tawarova raménka patofyziologie terapie MeSH
- elektrokardiografie metody MeSH
- Hisův svazek fyziologie MeSH
- kardiostimulace umělá metody MeSH
- lidé MeSH
- převodní systém srdeční patofyziologie MeSH
- senioři MeSH
- srdeční frekvence fyziologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
BACKGROUND: Early recognition and specific therapy facilitate a favorable disease course in hepatic venous-occlusive disease (HVOD) following hematopoietic stem cell transplantation (HCT). Diagnostic and classification criteria, published by the European Society for Blood and Marrow Transplantation (EBMT), better account for clinical differences in disease presentation in pediatric populations. OBJECTIVES: To compare the course of HVOD in children before and after the implementation of new EBMT criteria. MATERIAL AND METHODS: The study retrospectively evaluates 26 HVODs in 179 children treated in a single HCT unit (Slovakia) comparing the period of 2014-2017 using the Baltimore and modified Seattle criteria with the period of 2018-2021, when new EBMT criteria were adopted. RESULTS: No difference in HVOD incidence (11.2% vs. 14.8%, p = 0.46) and in time of diagnosis post-HCT (15.6 days vs. 15.7 days, p = 0.75) was found. With EBMT criteria we observed more frequent anicteric disease at diagnosis (50% vs. 87.5%, p = 0.04), lower serum bilirubin at diagnosis (3.4 mg/dL vs. 1.23 mg/dL, p = 0.045), and non-significant trends of shorter defibrotide treatment (21.7 days vs. 15.6 days, p = 0.73), decreased mortality (30% vs. 6.2%, p = 0.10) and shorter hospitalization (73.1 days vs. 59.6 days, p = 0.54). CONCLUSIONS: Different time periods around the implementation of new criteria are evaluated, underling that pediatric EBMT criteria for post-transplant HVOD diagnosis appear more sensitive.
