• Klíčová slova
• KIDNEY FUNCTION TESTS/in infancy and childhood *, URINARY CALCULI/in infancy and childhood *,
• MeSH
• dítě MeSH
• fyziologie močového ústrojí * MeSH
• kojenec MeSH
• lidé MeSH
• močové kameny * MeSH
• nefrolitiáza * MeSH
• vyšetření funkce ledvin * MeSH
• Check Tag
• dítě MeSH
• kojenec MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• dechová cvičení MeSH
• dýchání účinky léků   MeSH
• fyziologie dýchací soustavy * MeSH
• lidé MeSH
• morfin farmakologie   MeSH
• postura těla * MeSH
• respirační funkční testy MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• morfin MeSH

• Klíčová slova
• KIDNEY DISEASES/physiology *, KIDNEY FUNCTION TESTS *, OSMOSIS *,
• MeSH
• chronická renální insuficience * MeSH
• fyziologie močového ústrojí * MeSH
• lidé MeSH
• nemoci ledvin fyziologie   MeSH
• osmóza * MeSH
• vyšetření funkce ledvin * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

High-throughput profiling of key enzyme activities of carbon, nitrogen, and antioxidant metabolism is emerging as a valuable approach to integrate cell physiological phenotyping into a holistic functional phenomics approach. However, the analyses of the large datasets generated by this method represent a bottleneck, often keeping researchers from exploiting the full potential of their studies. We address these limitations through the exemplary application of a set of data evaluation and visualization tools within a case study. This includes the introduction of multivariate statistical analyses that can easily be implemented in similar studies, allowing researchers to extract more valuable information to identify enzymatic biosignatures. Through a literature meta-analysis, we demonstrate how enzyme activity profiling has already provided functional information on the mechanisms regulating plant development and response mechanisms to abiotic stress and pathogen attack. The high robustness of the distinct enzymatic biosignatures observed during developmental processes and under stress conditions underpins the enormous potential of enzyme activity profiling for future applications in both basic and applied research. Enzyme activity profiling will complement molecular -omics approaches to contribute to the mechanistic understanding required to narrow the genotype-to-phenotype knowledge gap and to identify predictive biomarkers for plant breeding to develop climate-resilient crops.

• Klíčová slova
• Abiotic stress response, enzyme activity profiling, enzyme activity signatures, functional phenomics, pathogen response, physiological phenotyping, plant development, plant phenotyping,
• MeSH
• fenomika * MeSH
• fenotyp MeSH
• fyziologický stres genetika   MeSH
• šlechtění rostlin * MeSH
• vývoj rostlin genetika   MeSH
• zemědělské plodiny genetika   MeSH
• Publikační typ
• časopisecké články MeSH
• metaanalýza MeSH
• práce podpořená grantem MeSH

• Klíčová slova
• DUST *, LUNG/physiology *,
• MeSH
• fyziologie dýchací soustavy * MeSH
• plíce fyziologie   MeSH
• prach * MeSH
• respirační funkční testy * MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• prach * MeSH

• Klíčová slova
• AUTONOMIC NERVOUS SYSTEM *, KIDNEY FUNCTION TESTS *, STRESS *, THIOPENTAL *,
• MeSH
• anestezie * MeSH
• anesteziologie * MeSH
• autonomní nervový systém * MeSH
• emoce * MeSH
• fyziologický stres * MeSH
• lidé MeSH
• thiopental * MeSH
• vyšetření funkce ledvin * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• thiopental * MeSH

Pulmonary congestion due to heart failure causes abnormal lung function. Cardiac resynchronization therapy (CRT) is a proven effective treatment for heart failure. The aim of this study was to test the hypothesis that CRT promotes increased lung volumes, bronchial conductance, and gas diffusion. Forty-four consecutive patients with heart failure were prospectively investigated before and after CRT. Spirometry, gas diffusion (diffusing capacity for carbon monoxide), cardiopulmonary exercise testing, New York Heart Association class, brain natriuretic peptide, the left ventricular ejection fraction, left atrial volume, and right ventricular systolic pressure were assessed before and 4 to 6 months after CRT. Pre- and post-CRT measures were compared using either paired Student's t tests or Wilcoxon's matched-pair test; p values <0.05 were considered significant. Improved New York Heart Association class, left ventricular ejection fraction, left atrial volume, right ventricular systolic pressure, and brain natriuretic peptide were observed after CRT (p <0.05 for all). Spirometry after CRT demonstrated increased percentage predicted total lung capacity (90 ± 17% vs 96 ± 15%, p <0.01) and percentage predicted forced vital capacity (80 ± 19% vs 90 ± 19%, p <0.01). Increased percentage predicted total lung capacity was significantly correlated with increased peak exercise end-tidal carbon dioxide (r = 0.43, p = 0.05). Increased percentage predicted forced vital capacity was significantly correlated with decreased right ventricular systolic pressure (r = -0.30, p = 0.05), body mass index (r = -0.35, p = 0.02) and creatinine (r = -0.49, p = 0.02), consistent with an association of improved bronchial conductance and decreased congestion. Diffusing capacity for carbon monoxide did not significantly change. In conclusion, increased lung volumes and bronchial conductance due to decreased pulmonary congestion and increased intrathoracic space contribute to an improved breathing pattern and decreased hyperventilation after CRT. Persistent alveolar-capillary membrane remodeling may account for unchanged diffusing capacity for carbon monoxide.

• MeSH
• fyziologie dýchací soustavy * MeSH
• lidé MeSH
• následné studie MeSH
• plíce patofyziologie   MeSH
• prognóza MeSH
• respirační funkční testy MeSH
• respirační insuficience etiologie   patofyziologie   MeSH
• senioři MeSH
• srdeční resynchronizační terapie metody   MeSH
• srdeční selhání komplikace   patofyziologie   terapie   MeSH
• stupeň závažnosti nemoci MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Research Support, N.I.H., Extramural MeSH
• srovnávací studie MeSH

• Klíčová slova
• PNEUMOCONIOSIS *, RESPIRATORY FUNCTION TESTS *,
• MeSH
• fyziologie dýchací soustavy * MeSH
• lidé MeSH
• plíce * MeSH
• pneumokonióza * MeSH
• respirační funkční testy * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

• Klíčová slova
• LUNGS/physiology *,
• MeSH
• fyziologie dýchací soustavy * MeSH
• lidé MeSH
• plíce fyziologie   MeSH
• respirační funkční testy * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

Arbuscular mycorrhizal fungi (AMF) have been widely reported to occur in the association with wetland plants. However, the factors that affect AMF colonization in wetland plants and physiological functions in AMF inoculated wetland plants are poorly studied. This study investigated the effects of four water regimes (below the surface of sands: water levels of 5 cm, 9 cm, 11 cm, and fluctuating water depth (9-11 cm)) on AMF root colonization in two wetland plants (Phalaris arundinacea and Scirpus sylvaticus) which are commonly used in constructed wetland. Results showed that two lower water regimes were the most suitable for the formation of root colonization by AMF. Plant species did not show any significant difference in AMF colonization. The AMF colonization of 15.6-23.3% in the roots of both wetland plants were determined under the water regimes of 11 cm and 9-11 cm. In comparison to the non-inoculated plants, root length, shoot height, biomass, shoot total phosphorus and chlorophyll contents of both wetland plants under the fluctuating water regimes (9-11 cm) were increased by 35.4-46.2%, 13.1-26.6%, 33.3-114.3%, 25.7-80% and 14.3-24%, respectively. Although malondialdehyde (MDA) contents in both AMF inoculated wetland plants were decreased under the lower water levels, the MDA contents under the water regime of 11 cm were still high. Therefore, these results indicated that the physiological functions in wetland plants with high AMF colonization might be improved under a specific water regime condition (e.g. depth of fluctuating water regime).

• Klíčová slova
• Arbuscular mycorrhizal fungi, Colonization, Physiological function, Water regimes, Wetland plants,
• MeSH
• kořeny rostlin MeSH
• mokřady MeSH
• mykorhiza * MeSH
• rostliny MeSH
• voda MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• voda MeSH