BURGER\'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 1: Principles and Practice This new edition of Dr. Alfred Burger\'s internationally celebrated classic helps researchers acquaint themselves with both traditional and state-of-the-art principles and practices governing new drug research and development. Completely updated and revised to reflect the many monumental changes that have occurred over the past decade and a half in medicinal chemistry and new drug development, this latest edition of Volume 1: Principles and Practice now: * Covers the latest methods of drug discovery, including such \"hot\" topics as computational chemistry and peptidomimetrics * Has added emphasis on preclinical development issues * Offers the most timely information on a broad range of important regulatory, management, legal, and financial issues * Features in-depth coverage of important factors in the discovery process, including ADME, toxicity and drug allergy, and clinical trials * Updates readers on recent advances in the understanding of the structural biology of drug action * Explores the cutting-edge technologies for drug discovery now in use around the world * Is more than twice the size of its predecessor * Brings together contributions by experts in a wide range of related fields from North America and Europe

Principles and practice

Skrytá bibl. Index: s. 1035-1064