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Principy a využití kometové analýzy při detekci poškození DNA
[Principles and applications of the comet assay in detection of DNA damage]
Miroslav Dvořák, Milena Matejovičová
Language Czech Country Czech Republic
- MeSH
- Apoptosis immunology MeSH
- Financing, Organized MeSH
- Comet Assay methods utilization MeSH
- Mutagenesis genetics MeSH
- DNA Damage MeSH
This review provides a brief information on principles and possible applications of the comet assay method, known as single cell gel electrophoresis, allowing to analyze DNA damage. This method developed in the mid-seventies was widely used in the early eighties of the last century. Several modifications of the comet assay approach made this method an attractive tool in various fields such as molecular biology research, quality control, clinical diagnosis, and monitoring of environmental pollution.
Principles and applications of the comet assay in detection of DNA damage
Lit.: 66
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- $a Principles and applications of the comet assay in detection of DNA damage
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- $a Biochemický ústav, Lékařská fakulta, Masarykova univerzita, Brno
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- $a Lit.: 66
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- $a This review provides a brief information on principles and possible applications of the comet assay method, known as single cell gel electrophoresis, allowing to analyze DNA damage. This method developed in the mid-seventies was widely used in the early eighties of the last century. Several modifications of the comet assay approach made this method an attractive tool in various fields such as molecular biology research, quality control, clinical diagnosis, and monitoring of environmental pollution.
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