-
Something wrong with this record ?
5-lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents
Jampilek J, Dolezal M, Opletalova V, Hartl J
Language English Country Netherlands
Document type Review
NLK
ProQuest Central
from 2000-01-01 to 2008-12-31
Health & Medicine (ProQuest)
from 2000-01-01 to 2008-12-31
- MeSH
- Leukotriene Antagonists pharmacology MeSH
- Anti-Asthmatic Agents pharmacology MeSH
- Anti-Inflammatory Agents pharmacology MeSH
- Arachidonate 5-Lipoxygenase metabolism MeSH
- Financing, Organized MeSH
- Lipoxygenase Inhibitors MeSH
- Arachidonic Acids metabolism MeSH
- Leukotrienes biosynthesis MeSH
- Humans MeSH
- Substrate Specificity MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Review MeSH
Leukotrienes play an important role in the inflammatory process accompanying allergic diseases of respiratory, gastrointestinal and dermatological systems. Leukotrienes are generated from arachidonic acid as a result of the 5-lipoxygenase action. This paper deals with 5-lipoxygenase action mechanism and the following biosynthesis of all leukotrienes. In this article, potential antileukotrienic agents are classified according to their mechanism of action. The original antileukotrienic compounds of the Research Institute for Pharmacy and Biochemistry in Prague (VUFB), Czech Republic are presented in a separate chapter of the paper.
- 000
- 00000naa 2200000 a 4500
- 001
- bmc07520383
- 003
- CZ-PrNML
- 005
- 20120116183529.0
- 008
- 090401s2006 ne e eng||
- 009
- AR
- 040 __
- $a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ne
- 100 1_
- $a Jampílek, Josef $7 xx0027075
- 245 10
- $a 5-lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents / $c Jampilek J, Dolezal M, Opletalova V, Hartl J
- 314 __
- $a Zentiva a.s., U kabelovny 130, 102 37 Prague, Czech Republic. josef.jampilek@zentiva.cz
- 520 9_
- $a Leukotrienes play an important role in the inflammatory process accompanying allergic diseases of respiratory, gastrointestinal and dermatological systems. Leukotrienes are generated from arachidonic acid as a result of the 5-lipoxygenase action. This paper deals with 5-lipoxygenase action mechanism and the following biosynthesis of all leukotrienes. In this article, potential antileukotrienic agents are classified according to their mechanism of action. The original antileukotrienic compounds of the Research Institute for Pharmacy and Biochemistry in Prague (VUFB), Czech Republic are presented in a separate chapter of the paper.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a antiastmatika $x farmakologie $7 D018927
- 650 _2
- $a antiflogistika $x farmakologie $7 D000893
- 650 _2
- $a arachidonát-5-lipoxygenasa $x metabolismus $7 D001094
- 650 _2
- $a kyseliny arachidonové $x metabolismus $7 D001095
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a antagonisté leukotrienů $x farmakologie $7 D020024
- 650 _2
- $a leukotrieny $x biosyntéza $7 D015289
- 650 _2
- $a substrátová specifita $7 D013379
- 650 _2
- $a financování organizované $7 D005381
- 650 _2
- $a inhibitory lipoxygenas $7 D016859
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Doležal, Martin, $7 jn19981000714 $d 1961-
- 700 1_
- $a Opletalová, Veronika, $d 1955- $7 jn20000620259
- 700 1_
- $a Hartl, Jiří, $d 1938- $7 jn20000400894
- 773 0_
- $w MED00001274 $t Current medicinal chemistry $g Roč. 13, č. 2 (2006), s. 117-129 $x 0929-8673
- 910 __
- $a ABA008 $b x $y 9
- 990 __
- $a 20090312170439 $b ABA008
- 991 __
- $a 20120116183607 $b ABA008
- 999 __
- $a ok $b bmc $g 638186 $s 490985
- BAS __
- $a 3
- BMC __
- $a 2006 $b 13 $c 2 $d 117-129 $i 0929-8673 $m Current medicinal chemistry $x MED00001274
- LZP __
- $a 2009-B1/vtme