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Terlipressin-induced ventricular arrhythmia
J Urge, F Sincl, V Prochazka, K Urbanek
Language English Country Norway
Document type Case Reports
- MeSH
- Adult MeSH
- Electric Countershock MeSH
- Electrocardiography MeSH
- Gastrointestinal Hemorrhage diagnosis drug therapy MeSH
- Risk Assessment MeSH
- Infusions, Intravenous MeSH
- Humans MeSH
- Lypressin analogs & derivatives adverse effects therapeutic use MeSH
- Follow-Up Studies MeSH
- Severity of Illness Index MeSH
- Long QT Syndrome diagnosis chemically induced therapy MeSH
- Torsades de Pointes diagnosis chemically induced therapy MeSH
- Vasoconstrictor Agents adverse effects therapeutic use MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Case Reports MeSH
During intravenous treatment with terlipressin for recurrent gastrointestinal (GI) bleeding, a 50-year-old male with no history of heart disease developed a newly prolonged QT interval and torsade de pointes. Risk factors present for acquired long QT syndrome were mineral dysbalance and a history of alcohol abuse with hepatic impairment. The patient was brought back to a normal sinus rhythm after a single 300-J counter-shock. Terlipressin was discontinued, and the patient's QTc interval subsequently returned to baseline. During 6 weeks of monitoring, arrhythmia did not recur.
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- $a Department of Internal Medicine II, Faculty of Medicine and Dentistry, Palacky University, University Hospital, Olomouc, Czech Republic.
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- $a During intravenous treatment with terlipressin for recurrent gastrointestinal (GI) bleeding, a 50-year-old male with no history of heart disease developed a newly prolonged QT interval and torsade de pointes. Risk factors present for acquired long QT syndrome were mineral dysbalance and a history of alcohol abuse with hepatic impairment. The patient was brought back to a normal sinus rhythm after a single 300-J counter-shock. Terlipressin was discontinued, and the patient's QTc interval subsequently returned to baseline. During 6 weeks of monitoring, arrhythmia did not recur.
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