• Je něco špatně v tomto záznamu ?

Quantification through TLC-densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves

RS. Affonso, JA. Lima, BM. Lessa, JVO. Caetano, MT. Obara, AB. Nóbrega, E. Nepovimova, K. Musilek, K. Kuca, GBCA. Slana, TCC. França,

. 2018 ; 32 (2) : . [pub] 20171015

Jazyk angličtina Země Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc18010337

Grantová podpora
NV16-34390A MZ0 CEP - Centrální evidence projektů

The rise of the mosquitoes-transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased concerns on protection against mosquitoes bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed here the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as a repellent and its acetylcholinesterase (AChE) inhibition capacity. Our results have proved HPTLC-densitometry as an efficient and appropriate method for this quantification and confirmed the repellency activity, as well as its capacity of AChE inhibition.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18010337
003      
CZ-PrNML
005      
20180530144001.0
007      
ta
008      
180404s2018 xxk f 000 0|eng||
009      
AR
024    7_
$a 10.1002/bmc.4096 $2 doi
035    __
$a (PubMed)28913959
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxk
100    1_
$a Affonso, Raphael S $u Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense, Military Institute of Engineering, Rio de Janeiro, Brazil.
245    10
$a Quantification through TLC-densitometric analysis, repellency and anticholinesterase activity of the homemade extract of Indian cloves / $c RS. Affonso, JA. Lima, BM. Lessa, JVO. Caetano, MT. Obara, AB. Nóbrega, E. Nepovimova, K. Musilek, K. Kuca, GBCA. Slana, TCC. França,
520    9_
$a The rise of the mosquitoes-transmitted diseases, like dengue, zika and chikungunya in Brazil in the last years has increased concerns on protection against mosquitoes bites. However, the prohibitive prices of the commercially available repellents for the majority of the Brazilian population has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of Indian clove (Syzygium aromaticum L.) as repellent, which has been reported as quite efficient by the local press. In order to verify this, we performed here the quantification of the main components of this extract through high-performance thin-layer chromatography (HPTLC)-densitometry and evaluated its efficiency as a repellent and its acetylcholinesterase (AChE) inhibition capacity. Our results have proved HPTLC-densitometry as an efficient and appropriate method for this quantification and confirmed the repellency activity, as well as its capacity of AChE inhibition.
650    _2
$a acetylcholinesterasa $x metabolismus $7 D000110
650    _2
$a dospělí $7 D000328
650    _2
$a Aedes $x účinky léků $7 D000330
650    _2
$a zvířata $7 D000818
650    _2
$a chování zvířat $x účinky léků $7 D001522
650    12
$a cholinesterasové inhibitory $x analýza $x chemie $x farmakologie $7 D002800
650    _2
$a chromatografie na tenké vrstvě $x metody $7 D002855
650    _2
$a denzitometrie $7 D003720
650    _2
$a eugenol $x analýza $x chemie $x farmakologie $7 D005054
650    _2
$a lidé $7 D006801
650    12
$a repelenty proti hmyzu $x analýza $x chemie $x farmakologie $7 D007302
650    _2
$a limita detekce $7 D057230
650    _2
$a lineární modely $7 D016014
650    _2
$a mužské pohlaví $7 D008297
650    12
$a rostlinné extrakty $x analýza $x chemie $x farmakologie $7 D010936
650    _2
$a reprodukovatelnost výsledků $7 D015203
650    _2
$a Syzygium $x chemie $7 D027842
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
700    1_
$a Lima, Josélia A $u Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense, Military Institute of Engineering, Rio de Janeiro, Brazil.
700    1_
$a Lessa, Bruno M $u Biodiversity Chemistry Laboratory, Phytomedicine Agroecological Platform, Brazil.
700    1_
$a Caetano, João V O $u Anhanguera College of Brasília, Brazil.
700    1_
$a Obara, Marcos T $u University of Brasília, University of Brasilia, Nucleus of tropical medicine, Brazil.
700    1_
$a Nóbrega, Andréa B $u Biodiversity Chemistry Laboratory, Phytomedicine Agroecological Platform, Brazil.
700    1_
$a Nepovímová, Eugenie $u University Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic. $7 xx0224758
700    1_
$a Musilek, Kamil $u University Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic. University Hospital, Biomedical Research Centre, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
700    1_
$a Kuca, Kamil $u University Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic.
700    1_
$a Slana, Gláucia B C A $u Biodiversity Chemistry Laboratory, Phytomedicine Agroecological Platform, Brazil. National Institute of Intellectual Property, Brazil.
700    1_
$a França, Tanos C C $u Laboratory of Molecular Modeling Applied to the Chemical and Biological Defense, Military Institute of Engineering, Rio de Janeiro, Brazil. Center for Basic and Applied Research, Faculty of Informatics and Management, University of Hradec Kralove, Hradec Kralove, Czech Republic.
773    0_
$w MED00000817 $t BMC. Biomedical chromatography $x 1099-0801 $g Roč. 32, č. 2 (2018)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28913959 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20180404 $b ABA008
991    __
$a 20180530144156 $b ABA008
999    __
$a ok $b bmc $g 1287822 $s 1007149
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 32 $c 2 $e 20171015 $i 1099-0801 $m BMC. Biomedical chromatography $n Biomed Chromatogr $x MED00000817
GRA    __
$a NV16-34390A $p MZ0
LZP    __
$a Pubmed-20180404

Najít záznam

Citační ukazatele

Možnosti archivace