• Je něco špatně v tomto záznamu ?

Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry

P. Cermakova, M. Nelson, J. Secnik, S. Garcia-Ptacek, K. Johnell, J. Fastbom, L. Kilander, B. Winblad, M. Eriksdotter, D. Religa,

. 2017 ; 58 (4) : 1265-1272.

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc18024984

BACKGROUND: Many people with Alzheimer's disease (AD) live alone in their own homes. There is a lack of knowledge about whether these individuals receive the same quality of diagnostics and treatment for AD as patients who are cohabiting. OBJECTIVES: To investigate the diagnostic work-up and treatment of community-dwelling AD patients who live alone. METHODS: We performed a cross-sectional cohort study based on data from the Swedish Dementia Registry (SveDem). We studied patients diagnosed with AD between 2007 and 2015 (n = 26,163). Information about drugs and comorbidities was acquired from the Swedish Prescribed Drug Register and the Swedish Patient Register. RESULTS: 11,878 (46%) patients lived alone, primarily older women. After adjusting for confounders, living alone was inversely associated with receiving computed tomography (OR 0.90; 95% CI 0.82-0.99), magnetic resonance imaging (OR 0.91; 95% CI 0.83-0.99), and lumbar puncture (OR 0.86; 95% CI 0.80-0.92). Living alone was also negatively associated with the use of cholinesterase inhibitors (OR 0.81; 95% CI 0.76; 0.87), memantine (OR 0.77; 95% CI 0.72; 0.83), and cardiovascular medication (OR 0.92; 0.86; 0.99). On the other hand, living alone was positively associated with the use of antidepressants (OR 1.15; 95% CI 1.08; 1.22), antipsychotics (OR 1.41; 95% CI 1.25; 1.58), and hypnotics and sedatives (OR 1.09; 95% CI 1.02; 1.17). CONCLUSIONS: Solitary living AD patients do not receive the same extent of care as those who are cohabiting.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18024984
003      
CZ-PrNML
005      
20180713111957.0
007      
ta
008      
180709s2017 ne f 000 0|eng||
009      
AR
024    7_
$a 10.3233/JAD-170102 $2 doi
035    __
$a (PubMed)28550260
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a ne
100    1_
$a Cermakova, Pavla $u Department of Neurobiology, Care Sciences andSociety, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Stockholm, Sweden. National Instituteof Mental Health, Klecany, Czech Republic.
245    10
$a Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry / $c P. Cermakova, M. Nelson, J. Secnik, S. Garcia-Ptacek, K. Johnell, J. Fastbom, L. Kilander, B. Winblad, M. Eriksdotter, D. Religa,
520    9_
$a BACKGROUND: Many people with Alzheimer's disease (AD) live alone in their own homes. There is a lack of knowledge about whether these individuals receive the same quality of diagnostics and treatment for AD as patients who are cohabiting. OBJECTIVES: To investigate the diagnostic work-up and treatment of community-dwelling AD patients who live alone. METHODS: We performed a cross-sectional cohort study based on data from the Swedish Dementia Registry (SveDem). We studied patients diagnosed with AD between 2007 and 2015 (n = 26,163). Information about drugs and comorbidities was acquired from the Swedish Prescribed Drug Register and the Swedish Patient Register. RESULTS: 11,878 (46%) patients lived alone, primarily older women. After adjusting for confounders, living alone was inversely associated with receiving computed tomography (OR 0.90; 95% CI 0.82-0.99), magnetic resonance imaging (OR 0.91; 95% CI 0.83-0.99), and lumbar puncture (OR 0.86; 95% CI 0.80-0.92). Living alone was also negatively associated with the use of cholinesterase inhibitors (OR 0.81; 95% CI 0.76; 0.87), memantine (OR 0.77; 95% CI 0.72; 0.83), and cardiovascular medication (OR 0.92; 0.86; 0.99). On the other hand, living alone was positively associated with the use of antidepressants (OR 1.15; 95% CI 1.08; 1.22), antipsychotics (OR 1.41; 95% CI 1.25; 1.58), and hypnotics and sedatives (OR 1.09; 95% CI 1.02; 1.17). CONCLUSIONS: Solitary living AD patients do not receive the same extent of care as those who are cohabiting.
650    _2
$a senioři $7 D000368
650    _2
$a senioři nad 80 let $7 D000369
650    _2
$a Alzheimerova nemoc $x farmakoterapie $x epidemiologie $x psychologie $7 D000544
650    _2
$a antidepresiva $7 D000928
650    _2
$a antipsychotika $x terapeutické užití $7 D014150
650    _2
$a kohortové studie $7 D015331
650    _2
$a komorbidita $7 D015897
650    _2
$a demence $x epidemiologie $x psychologie $7 D003704
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a samostatný způsob života $7 D057187
650    _2
$a magnetická rezonanční tomografie $7 D008279
650    _2
$a mužské pohlaví $7 D008297
650    12
$a registrace $7 D012042
650    12
$a sociální podmínky $7 D012924
650    _2
$a Švédsko $x epidemiologie $7 D013548
655    _2
$a časopisecké články $7 D016428
700    1_
$a Nelson, Maja $u Department of Neurobiology, Care Sciences andSociety, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Stockholm, Sweden.
700    1_
$a Secnik, Juraj $u Department of Neurobiology, Care Sciences andSociety, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Stockholm, Sweden.
700    1_
$a Garcia-Ptacek, Sara $u Department of Neurobiology, Care Sciences andSociety, Division of Clinical Geriatrics, Karolinska Institutet, Huddinge, Sweden. Department of Geriatric Medicine, Karolinska University Hospital, Stockholm, Sweden. Södersjukhuset, Department of Internal Medicine, Neurology, Stockholm, Sweden.
700    1_
$a Johnell, Kristina $u Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
700    1_
$a Fastbom, Johan $u Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
700    1_
$a Kilander, Lena $u Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.
700    1_
$a Winblad, Bengt $u Department of Neurobiology, Care Sciences andSociety, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Stockholm, Sweden. Department of Geriatric Medicine, Karolinska University Hospital, Stockholm, Sweden.
700    1_
$a Eriksdotter, Maria $u Department of Neurobiology, Care Sciences andSociety, Division of Clinical Geriatrics, Karolinska Institutet, Huddinge, Sweden. Department of Geriatric Medicine, Karolinska University Hospital, Stockholm, Sweden.
700    1_
$a Religa, Dorota $u Department of Neurobiology, Care Sciences andSociety, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Stockholm, Sweden. Department of Geriatric Medicine, Karolinska University Hospital, Stockholm, Sweden.
773    0_
$w MED00006350 $t Journal of Alzheimer's disease JAD $x 1875-8908 $g Roč. 58, č. 4 (2017), s. 1265-1272
856    41
$u https://pubmed.ncbi.nlm.nih.gov/28550260 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20180709 $b ABA008
991    __
$a 20180713112251 $b ABA008
999    __
$a ok $b bmc $g 1317115 $s 1021905
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2017 $b 58 $c 4 $d 1265-1272 $i 1875-8908 $m Journal of Alzheimer's disease $n J Alzheimers Dis $x MED00006350
LZP    __
$a Pubmed-20180709

Najít záznam

Citační ukazatele

Možnosti archivace