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Nature-derived microbiota exposure as a novel immunomodulatory approach
N. Nurminen, J. Lin, M. Grönroos, R. Puhakka, L. Kramna, HK. Vari, H. Viskari, S. Oikarinen, M. Roslund, A. Parajuli, I. Tyni, O. Cinek, O. Laitinen, H. Hyöty, A. Sinkkonen,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu klinické zkoušky, časopisecké články, práce podpořená grantem
NLK
PubMed Central
od 2015 do Před 1 rokem
ProQuest Central
od 2006-06-01 do 2020-07-31
Nursing & Allied Health Database (ProQuest)
od 2006-06-01 do 2020-07-31
Health & Medicine (ProQuest)
od 2006-06-01 do 2020-07-31
Public Health Database (ProQuest)
od 2006-06-01 do 2020-07-31
PubMed
29771153
DOI
10.2217/fmb-2017-0286
Knihovny.cz E-zdroje
- MeSH
- Bacteria klasifikace genetika izolace a purifikace MeSH
- biodiverzita MeSH
- dospělí MeSH
- feces mikrobiologie MeSH
- gastrointestinální trakt imunologie mikrobiologie MeSH
- imunita * MeSH
- imunomodulace MeSH
- kůže imunologie mikrobiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- pilotní projekty MeSH
- půda chemie MeSH
- půdní mikrobiologie * MeSH
- rostliny mikrobiologie MeSH
- střevní mikroflóra * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky MeSH
- práce podpořená grantem MeSH
AIM: Current attempts to modulate the human microbiota and immune responses are based on probiotics or human-derived bacterial transplants. We investigated microbial modulation by soil and plant-based material. MATERIALS & METHODS: We performed a pilot study in which healthy adults were exposed to the varied microbial community of a soil- and plant-based material. RESULTS: The method was safe and feasible; exposure was associated with an increase in gut microbial diversity. CONCLUSION: If these findings are reproduced in larger studies nature-derived microbial exposure strategies could be further developed for testing their efficacy in the treatment and prevention of immune-mediated diseases.
Citace poskytuje Crossref.org
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- $a AIM: Current attempts to modulate the human microbiota and immune responses are based on probiotics or human-derived bacterial transplants. We investigated microbial modulation by soil and plant-based material. MATERIALS & METHODS: We performed a pilot study in which healthy adults were exposed to the varied microbial community of a soil- and plant-based material. RESULTS: The method was safe and feasible; exposure was associated with an increase in gut microbial diversity. CONCLUSION: If these findings are reproduced in larger studies nature-derived microbial exposure strategies could be further developed for testing their efficacy in the treatment and prevention of immune-mediated diseases.
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