-
Je něco špatně v tomto záznamu ?
Complications and mortality of surgical therapy for esophageal cancer: 10 years single center experience
R. Vrba, D. Vrana, C. Neoral, R. Aujesky, M. Stasek, T. Bohanes, J. Tesarikova, J. Cincibuch, B. Melichar, M. Horakova, J. Zapletalova
Jazyk angličtina Země Slovensko
- MeSH
- adenokarcinom chirurgie mortalita MeSH
- ezofagektomie metody škodlivé účinky MeSH
- gastroplastika MeSH
- lidé středního věku MeSH
- lidé MeSH
- miniinvazivní chirurgické výkony MeSH
- nádory jícnu * diagnóza chirurgie mortalita radioterapie MeSH
- neoadjuvantní terapie MeSH
- peroperační komplikace MeSH
- retrospektivní studie MeSH
- spinocelulární karcinom chirurgie mortalita MeSH
- staging nádorů MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
A single-center retrospective study the complication and mortality of surgical treatment of esophageal cancer 2006 to 2015 is presented. A total of 212 patients with esophageal cancer were operated at the First Department of Surgery University Hospital Olomouc, Czech Republic in the period between 2006 and 2015. Adenocarcinoma was histologically described in 127 patients (59.9%), squamous cell carcinoma in 82 patients (38.7%), and other types of carcinoma were described in 3 cases. According to the preoperative staging of esophageal cancer, the patients with early stage disease (T1-2N0M0) had primary surgery, while the patients with advanced stage (T3-4N0-2M0) were indicated for neoadjuvant chemoradiation with the surgery being performed subsequently. Transhiatal laparoscopic esophagectomy was performed in 183 patients, and Orringer esophagectomy in 4 patients. Thoracoscopic esophagectomy was performed in 17 patients and thoracotomy in 30 patients. Respiratory failure with the development of ARDS syndrome accompanied by multiple-organ failure occurred in 21 patients. Statistically significant association between mortality and ASA (p = 0.009) and between respiratory complications and ASA (p = 0.006) was demonstrated. The majority of patients who died were under 60 years of age (p = 0.039). Further, significant association between 30-day mortality and tumor stage (p = 0.021), gender (p = 0.022) and age (p = 0.018) was evident. A significant association between tumor stage and fistula in anastomosis, (p = 0.043) was observed. Esophagectomy is a procedure, which should be performed in specialized high-volume centers experienced in treatment of this serious malignancy and by certified oncology surgeons with long time experience in esophageal surgery.
Citace poskytuje Crossref.org
Literatura
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19005386
- 003
- CZ-PrNML
- 005
- 20191017144942.0
- 007
- ta
- 008
- 190205s2018 xo f 000 0|eng||
- 009
- AR
- 024 0_
- $a 10.4149/neo_2018_171013N651 $2 doi
- 040 __
- $a ABA008 $d ABA008 $e AACR2 $b cze
- 041 0_
- $a eng
- 044 __
- $a xo
- 100 1_
- $a Vrba, Radek $7 xx0062746 $u First Department of Surgery, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 245 10
- $a Complications and mortality of surgical therapy for esophageal cancer: 10 years single center experience / $c R. Vrba, D. Vrana, C. Neoral, R. Aujesky, M. Stasek, T. Bohanes, J. Tesarikova, J. Cincibuch, B. Melichar, M. Horakova, J. Zapletalova
- 504 __
- $a Literatura
- 520 __
- $a A single-center retrospective study the complication and mortality of surgical treatment of esophageal cancer 2006 to 2015 is presented. A total of 212 patients with esophageal cancer were operated at the First Department of Surgery University Hospital Olomouc, Czech Republic in the period between 2006 and 2015. Adenocarcinoma was histologically described in 127 patients (59.9%), squamous cell carcinoma in 82 patients (38.7%), and other types of carcinoma were described in 3 cases. According to the preoperative staging of esophageal cancer, the patients with early stage disease (T1-2N0M0) had primary surgery, while the patients with advanced stage (T3-4N0-2M0) were indicated for neoadjuvant chemoradiation with the surgery being performed subsequently. Transhiatal laparoscopic esophagectomy was performed in 183 patients, and Orringer esophagectomy in 4 patients. Thoracoscopic esophagectomy was performed in 17 patients and thoracotomy in 30 patients. Respiratory failure with the development of ARDS syndrome accompanied by multiple-organ failure occurred in 21 patients. Statistically significant association between mortality and ASA (p = 0.009) and between respiratory complications and ASA (p = 0.006) was demonstrated. The majority of patients who died were under 60 years of age (p = 0.039). Further, significant association between 30-day mortality and tumor stage (p = 0.021), gender (p = 0.022) and age (p = 0.018) was evident. A significant association between tumor stage and fistula in anastomosis, (p = 0.043) was observed. Esophagectomy is a procedure, which should be performed in specialized high-volume centers experienced in treatment of this serious malignancy and by certified oncology surgeons with long time experience in esophageal surgery.
- 650 12
- $a nádory jícnu $x diagnóza $x chirurgie $x mortalita $x radioterapie $7 D004938
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 _2
- $a neoadjuvantní terapie $7 D020360
- 650 _2
- $a ezofagektomie $x metody $x škodlivé účinky $7 D016629
- 650 _2
- $a miniinvazivní chirurgické výkony $7 D019060
- 650 _2
- $a gastroplastika $7 D015391
- 650 _2
- $a peroperační komplikace $7 D007431
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a adenokarcinom $x chirurgie $x mortalita $7 D000230
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a staging nádorů $7 D009367
- 650 _2
- $a spinocelulární karcinom $x chirurgie $x mortalita $7 D002294
- 700 1_
- $a Vrana, D. $u Department of Oncology, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Neoral, Čestmír, $d 1952- $7 xx0000421 $u First Department of Surgery, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Aujeský, René $7 xx0073000 $u First Department of Surgery, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Stašek, Martin $7 xx0141653 $u First Department of Surgery, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Bohanes, Tomáš $7 xx0033707 $u First Department of Surgery, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Tesarikova, J. $u First Department of Surgery, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Cincibuch, Jan $7 xx0135583 $u Department of Oncology, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Melichar, Bohuslav, $d 1965- $7 skuk0000853 $u Department of Oncology, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Horáková, Martina $7 xx0110489 $u Department of Surgical Intensive Care, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 700 1_
- $a Zapletalová, Jana $7 xx0111614 $u Department of Biophysics, Faculty of Medicine and Dentistry and University Hospital Olomouc, Czech Republic
- 773 0_
- $t Neoplasma $x 0028-2685 $g Roč. 65, č. 5 (2018), s. 799-806 $w MED00003470
- 910 __
- $a ABA008 $b A 1194 $c 659 $y 4 $z 0
- 990 __
- $a 20190205091035 $b ABA008
- 991 __
- $a 20191017145410 $b ABA008
- 999 __
- $a ok $b bmc $g 1374013 $s 1043591
- BAS __
- $a 3
- BMC __
- $a 2018 $b 65 $c 5 $d 799-806 $i 0028-2685 $m Neoplasma $x MED00003470
- LZP __
- $c NLK182 $d 20190313 $a NLK 2019-10/pk
