-
Something wrong with this record ?
Anaplastic Large-Cell Lymphoma Associated with Breast Implants: A Case Report of a Transgender Female
M. Patzelt, L. Zarubova, P. Klener, J. Barta, K. Benkova, A. Brandejsova, M. Trneny, R. Gürlich, A. Sukop,
Language English Country United States
Document type Case Reports, Journal Article
NLK
ProQuest Central
from 2002-11-01 to 1 year ago
Medline Complete (EBSCOhost)
from 2003-01-01 to 1 year ago
Health & Medicine (ProQuest)
from 2002-11-01 to 1 year ago
- MeSH
- Lymphoma, Large-Cell, Anaplastic diagnostic imaging etiology therapy MeSH
- Cyclophosphamide MeSH
- Doxorubicin MeSH
- Breast Implantation adverse effects methods MeSH
- Immunohistochemistry MeSH
- Biopsy, Needle MeSH
- Combined Modality Therapy MeSH
- Humans MeSH
- Magnetic Resonance Imaging methods MeSH
- Breast Neoplasms diagnostic imaging etiology therapy MeSH
- Follow-Up Studies MeSH
- Device Removal MeSH
- Positron Emission Tomography Computed Tomography MeSH
- Prednisone MeSH
- Antineoplastic Combined Chemotherapy Protocols MeSH
- Breast Implants adverse effects MeSH
- Silicone Gels adverse effects MeSH
- Transgender Persons MeSH
- Vincristine MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare peripheral T cell lymphoma. BIA-ALCL is a disease of the fibrous capsule surrounding the implant and occurs in patients after both breast reconstruction and augmentation. More than 300 cases have been reported so far, including two in a transgender patient. Here we describe BIA-ALCL presented with a mass in a transgender patient and the first case of BIA-ALCL in the Czech Republic. In 2007, a 33-year-old transgender male to female underwent bilateral breast augmentation as a part of his transformation to female. In June 2014, the patient developed a 5-cm tumorous mass in her left breast. Magnetic resonance imaging of the chest revealed a ruptured implant and a tumorous mass penetrating into the capsule and infiltrating the pectoral muscle. An R0 surgery was indicated-the implant, silicone gel and capsule were removed, and the tumorous mass was resected together with a part of the pectoral muscle. Histology revealed anaplastic large-cell lymphoma. The patient underwent standard staging procedures for lymphoma including a bone marrow trephine biopsy, which confirmed stage IE. The patient was treated with the standard chemotherapy for systemic ALCL-6 cycles of CHOP-21. The patient was tumor-free at the 2-year follow-up. BIA-ALCL has been reported mostly in women who received implants for either reconstructive or aesthetic augmentation. This is the third report of BIA-ALCL in a transgender person, the first in the Czech Republic. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19013028
- 003
- CZ-PrNML
- 005
- 20250319153743.0
- 007
- ta
- 008
- 190405s2018 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/s00266-017-1012-y $2 doi
- 035 __
- $a (PubMed)29101436
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Patzelt, Matej $u Department of Plastic Surgery, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic. Third Faculty of Medicine, Charles University, Ruska 87, 100 00, Prague, Czech Republic.
- 245 10
- $a Anaplastic Large-Cell Lymphoma Associated with Breast Implants: A Case Report of a Transgender Female / $c M. Patzelt, L. Zarubova, P. Klener, J. Barta, K. Benkova, A. Brandejsova, M. Trneny, R. Gürlich, A. Sukop,
- 520 9_
- $a Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare peripheral T cell lymphoma. BIA-ALCL is a disease of the fibrous capsule surrounding the implant and occurs in patients after both breast reconstruction and augmentation. More than 300 cases have been reported so far, including two in a transgender patient. Here we describe BIA-ALCL presented with a mass in a transgender patient and the first case of BIA-ALCL in the Czech Republic. In 2007, a 33-year-old transgender male to female underwent bilateral breast augmentation as a part of his transformation to female. In June 2014, the patient developed a 5-cm tumorous mass in her left breast. Magnetic resonance imaging of the chest revealed a ruptured implant and a tumorous mass penetrating into the capsule and infiltrating the pectoral muscle. An R0 surgery was indicated-the implant, silicone gel and capsule were removed, and the tumorous mass was resected together with a part of the pectoral muscle. Histology revealed anaplastic large-cell lymphoma. The patient underwent standard staging procedures for lymphoma including a bone marrow trephine biopsy, which confirmed stage IE. The patient was treated with the standard chemotherapy for systemic ALCL-6 cycles of CHOP-21. The patient was tumor-free at the 2-year follow-up. BIA-ALCL has been reported mostly in women who received implants for either reconstructive or aesthetic augmentation. This is the third report of BIA-ALCL in a transgender person, the first in the Czech Republic. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
- 650 _2
- $a protokoly protinádorové kombinované chemoterapie $7 D000971
- 650 _2
- $a jehlová biopsie $7 D001707
- 650 _2
- $a implantace prsní náhrady $x škodlivé účinky $x metody $7 D019928
- 650 _2
- $a prsní implantáty $x škodlivé účinky $7 D018427
- 650 _2
- $a nádory prsu $x diagnostické zobrazování $x etiologie $x terapie $7 D001943
- 650 _2
- $a kombinovaná terapie $7 D003131
- 650 _2
- $a cyklofosfamid $7 D003520
- 650 _2
- $a odstranění implantátu $7 D020878
- 650 _2
- $a doxorubicin $7 D004317
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a následné studie $7 D005500
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a imunohistochemie $7 D007150
- 650 _2
- $a anaplastický velkobuněčný lymfom $x diagnostické zobrazování $x etiologie $x terapie $7 D017728
- 650 _2
- $a magnetická rezonanční tomografie $x metody $7 D008279
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a PET/CT $7 D000072078
- 650 _2
- $a prednison $7 D011241
- 650 _2
- $a silikonové gely $x škodlivé účinky $7 D020034
- 650 _2
- $a transgender osoby $7 D063106
- 650 _2
- $a výsledek terapie $7 D016896
- 650 _2
- $a vinkristin $7 D014750
- 655 _2
- $a kazuistiky $7 D002363
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Zárubová, Lucie $u Department of Plastic Surgery, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic. lucie.zarubova@fnkv.cz. Department of General Surgery, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic. lucie.zarubova@fnkv.cz. $7 xx0253596
- 700 1_
- $a Klener, Pavel $u First Medical Department of Hematology, Charles University General, U Nemocnice 499/2, 128 08, Prague, Czech Republic. Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Katerinska 32, 121 08, Prague, Czech Republic.
- 700 1_
- $a Bárta, Josef $7 xx0240651 $u Department of Radiology, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic.
- 700 1_
- $a Benkova, Kamila $u Department of Pathology in Prague, AeskuLab Pathology, Evropska 2589/33b, 100 06, Prague, Czech Republic.
- 700 1_
- $a Brandejsová, Adriana $7 xx0239875 $u Department of Plastic Surgery, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic.
- 700 1_
- $a Trneny, Marek $u First Medical Department of Hematology, Charles University General, U Nemocnice 499/2, 128 08, Prague, Czech Republic.
- 700 1_
- $a Gürlich, Robert $u Third Faculty of Medicine, Charles University, Ruska 87, 100 00, Prague, Czech Republic. Department of General Surgery, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic.
- 700 1_
- $a Sukop, Andrej $u Department of Plastic Surgery, Royal Vinohrady Teaching Hospital, Srobarova 1150/50, 100 34, Prague, Czech Republic. Third Faculty of Medicine, Charles University, Ruska 87, 100 00, Prague, Czech Republic.
- 773 0_
- $w MED00005691 $t Aesthetic plastic surgery $x 1432-5241 $g Roč. 42, č. 2 (2018), s. 451-455
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/29101436 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20190405 $b ABA008
- 991 __
- $a 20250319153738 $b ABA008
- 999 __
- $a ok $b bmc $g 1392338 $s 1051333
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2018 $b 42 $c 2 $d 451-455 $e 20171103 $i 1432-5241 $m Aesthetic plastic surgery $n Aesthetic Plast Surg $x MED00005691
- LZP __
- $a Pubmed-20190405
