Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck

PG. Flammer, S. Dellicour, SG. Preston, D. Rieger, S. Warren, CKW. Tan, R. Nicholson, R. Přichystalová, N. Bleicher, J. Wahl, NR. Faria, OG. Pybus, M. Pollard, AL. Smith,

. 2018 ; 285 (1888) : . [pub] 20181003

Language English Country England, Great Britain

Document type Historical Article, Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc19034980

Grant support
204311/Z/16/Z Wellcome Trust - United Kingdom
BB/K004468/1 Biotechnology and Biological Sciences Research Council - United Kingdom
BB/K001388/1 Biotechnology and Biological Sciences Research Council - United Kingdom

Throughout history, humans have been afflicted by parasitic worms, and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular archaeoparasitology as a new approach to study the past. Molecular analyses provided unequivocal species-level parasite identification and revealed location-specific epidemiological signatures. Faecal-oral transmitted nematodes (Ascaris lumbricoides and Trichuris trichiura) were ubiquitous across time and space. By contrast, high numbers of food-associated cestodes (Diphyllobothrium latum and Taenia saginata) were restricted to medieval Lübeck. The presence of these cestodes and changes in their prevalence at approximately 1300 CE indicate substantial alterations in diet or parasite availability. Trichuris trichiura ITS-1 sequences grouped into two clades; one ubiquitous and one restricted to medieval Lübeck and Bristol. The high sequence diversity of T.tITS-1 detected in Lübeck is consistent with its importance as a Hanseatic trading centre. Collectively, these results introduce molecular archaeoparasitology as an artefact-independent source of historical evidence.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19034980
003      
CZ-PrNML
005      
20191015123435.0
007      
ta
008      
191007s2018 enk f 000 0|eng||
009      
AR
024    7_
$a 10.1098/rspb.2018.0991 $2 doi
035    __
$a (PubMed)30282648
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Flammer, Patrik G $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK. Research Laboratory for Archaeology and the History of Art, University of Oxford, Oxford OX1 3QY, UK.
245    10
$a Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck / $c PG. Flammer, S. Dellicour, SG. Preston, D. Rieger, S. Warren, CKW. Tan, R. Nicholson, R. Přichystalová, N. Bleicher, J. Wahl, NR. Faria, OG. Pybus, M. Pollard, AL. Smith,
520    9_
$a Throughout history, humans have been afflicted by parasitic worms, and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular archaeoparasitology as a new approach to study the past. Molecular analyses provided unequivocal species-level parasite identification and revealed location-specific epidemiological signatures. Faecal-oral transmitted nematodes (Ascaris lumbricoides and Trichuris trichiura) were ubiquitous across time and space. By contrast, high numbers of food-associated cestodes (Diphyllobothrium latum and Taenia saginata) were restricted to medieval Lübeck. The presence of these cestodes and changes in their prevalence at approximately 1300 CE indicate substantial alterations in diet or parasite availability. Trichuris trichiura ITS-1 sequences grouped into two clades; one ubiquitous and one restricted to medieval Lübeck and Bristol. The high sequence diversity of T.tITS-1 detected in Lübeck is consistent with its importance as a Hanseatic trading centre. Collectively, these results introduce molecular archaeoparasitology as an artefact-independent source of historical evidence.
650    _2
$a zvířata $7 D000818
650    _2
$a archeologie $7 D001106
650    12
$a kulturní evoluce $7 D003468
650    _2
$a starobylá DNA $x analýza $7 D000072441
650    _2
$a feces $x parazitologie $7 D005243
650    _2
$a genetická variace $7 D014644
650    _2
$a cizopasní červi $x klasifikace $x fyziologie $7 D006376
650    _2
$a dějiny 15. století $7 D049668
650    _2
$a dějiny 16. století $7 D049669
650    _2
$a dějiny 17. století $7 D049670
650    _2
$a dějiny starověku $7 D049690
650    _2
$a dějiny středověku $7 D049691
650    _2
$a lidé $7 D006801
650    _2
$a počet parazitárních vajíček $7 D010270
650    _2
$a parazitologie $7 D010274
650    _2
$a trichurióza $x epidemiologie $x dějiny $x parazitologie $7 D014257
650    _2
$a Trichuris $x genetika $x fyziologie $7 D014258
651    _2
$a velkoměsta $x epidemiologie $7 D002947
651    _2
$a Německo $x epidemiologie $7 D005858
655    _2
$a historické články $7 D016456
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Dellicour, Simon $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK. Rega Institute for Medical Research, Clinical and Epidemiological Virology, Department of Microbiology and Immunology, KU Leuven-University of Leuven, 3000 Leuven, Belgium.
700    1_
$a Preston, Stephen G $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK.
700    1_
$a Rieger, Dirk $u Archäologie und Denkmalpflege der Hansestadt Lübeck, 23566 Lübeck, Germany.
700    1_
$a Warren, Sylvia $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK.
700    1_
$a Tan, Cedric K W $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK.
700    1_
$a Nicholson, Rebecca $u Oxford Archaeology Ltd., Janus House, Osney Mead, Oxford OX2 0ES, UK.
700    1_
$a Přichystalová, Renáta $u Masaryk University Brno, 60177 Brno, Czech Republic.
700    1_
$a Bleicher, Niels $u Hochbauamt der Stadt Zürich, Abteilung Unterwasserarchäologie, 8008 Zürich, Switzerland.
700    1_
$a Wahl, Joachim $u Universität Tübingen, 72070 Tübingen, Germany. Regierungspräsidium Stuttgart, Landesamt für Denkmalpflege, 78467 Konstanz, Germany.
700    1_
$a Faria, Nuno R $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK.
700    1_
$a Pybus, Oliver G $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK.
700    1_
$a Pollard, Mark $u Research Laboratory for Archaeology and the History of Art, University of Oxford, Oxford OX1 3QY, UK.
700    1_
$a Smith, Adrian L $u Department of Zoology, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford OX1 3SY, UK adrian.smith@zoo.ox.ac.uk.
773    0_
$w MED00012574 $t Proceedings. Biological sciences $x 1471-2954 $g Roč. 285, č. 1888 (2018)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30282648 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20191007 $b ABA008
991    __
$a 20191015123900 $b ABA008
999    __
$a ok $b bmc $g 1451640 $s 1073530
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 285 $c 1888 $e 20181003 $i 1471-2954 $m Proceedings - Royal Society. Biological sciences $n Proc R Soc Lond $x MED00012574
GRA    __
$a 204311/Z/16/Z $p Wellcome Trust $2 United Kingdom
GRA    __
$a BB/K004468/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
GRA    __
$a BB/K001388/1 $p Biotechnology and Biological Sciences Research Council $2 United Kingdom
LZP    __
$a Pubmed-20191007

Find record

Citation metrics

Archiving options