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Nucleoid-Associated Protein HU: A Lilliputian in Gene Regulation of Bacterial Virulence
P. Stojkova, P. Spidlova, J. Stulik,
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
NLK
Directory of Open Access Journals
od 2011
Free Medical Journals
od 2011
PubMed Central
od 2011
Europe PubMed Central
od 2011
Open Access Digital Library
od 2011-01-01
Open Access Digital Library
od 2011-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2011
PubMed
31134164
DOI
10.3389/fcimb.2019.00159
Knihovny.cz E-zdroje
- MeSH
- bakteriální proteiny chemie genetika metabolismus MeSH
- DNA bakterií metabolismus MeSH
- DNA vazebné proteiny chemie genetika metabolismus MeSH
- DNA chemie MeSH
- posttranslační úpravy proteinů MeSH
- regulace genové exprese u bakterií fyziologie MeSH
- vazba proteinů MeSH
- virulence genetika fyziologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
Nucleoid-associated proteins belong to a group of small but abundant proteins in bacterial cells. These transcription regulators are responsible for many important cellular processes and also are involved in pathogenesis of bacteria. The best-known nucleoid-associated proteins, such as HU, FIS, H-NS, and IHF, are often discussed. The most important findings in research concerning HU protein are described in this mini review. Its roles in DNA compaction, shape modulation, and negative supercoiling induction have been studied intensively. HU protein regulates bacteria survival, growth, SOS response, virulence genes expression, cell division, and many other cell processes. Elucidating the mechanism of HU protein action has been the subject of many research projects. This mini review provides a comprehensive overview of the HU protein.
Citace poskytuje Crossref.org
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