• Je něco špatně v tomto záznamu ?

Mechanical properties of a biodegradable self-expandable polydioxanone monofilament stent: In vitro force relaxation and its clinical relevance

A. Bezrouk, T. Hosszu, L. Hromadko, Z. Olmrova Zmrhalova, M. Kopecek, M. Smutny, I. Selke Krulichova, JM. Macak, J. Kremlacek,

. 2020 ; 15 (7) : e0235842. [pub] 20200708

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc20024894

Biodegradable stents are promising treatments for many diseases, e.g., coronary artery disease, urethral diseases, tracheal diseases, and esophageal strictures. The mechanical properties of biodegradable stent materials play a key role in the safety and efficacy of treatment. In particular, insufficient creep resistance of the stent material could result in premature stent collapse or narrowing. Commercially available biodegradable self-expandable SX-ELLA stents made of polydioxanone monofilament were tested. A new, simple, and affordable method to measure the shear modulus of tiny viscoelastic wires is presented. The important mechanical parameters of the polydioxanone filament were obtained: the median Young's modulus was [Formula: see text] = 958 (922, 974) MPa and the shear modulus was [Formula: see text] = 357 (185, 387) MPa, resulting in a Poisson's ratio of ν = 0.34. The SX-ELLA stents exhibited significant force relaxation due to the stress relaxation of the polydioxanone monofilament, approximately 19% and 36% 10 min and 48 h after stent application, respectively. However, these results were expected, and the manufacturer and implanting clinician should be aware of the known behavior of these biodegradable materials. If possible, a biodegradable stent should be designed considering therapeutic force rather than initial force. Additionally, new and more advanced biodegradable shape-memory polymers should be considered for future study and use.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc20024894
003      
CZ-PrNML
005      
20230428085544.0
007      
ta
008      
201125s2020 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1371/journal.pone.0235842 $2 doi
035    __
$a (PubMed)32639989
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Bezrouk, Ales $u Department of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
245    10
$a Mechanical properties of a biodegradable self-expandable polydioxanone monofilament stent: In vitro force relaxation and its clinical relevance / $c A. Bezrouk, T. Hosszu, L. Hromadko, Z. Olmrova Zmrhalova, M. Kopecek, M. Smutny, I. Selke Krulichova, JM. Macak, J. Kremlacek,
520    9_
$a Biodegradable stents are promising treatments for many diseases, e.g., coronary artery disease, urethral diseases, tracheal diseases, and esophageal strictures. The mechanical properties of biodegradable stent materials play a key role in the safety and efficacy of treatment. In particular, insufficient creep resistance of the stent material could result in premature stent collapse or narrowing. Commercially available biodegradable self-expandable SX-ELLA stents made of polydioxanone monofilament were tested. A new, simple, and affordable method to measure the shear modulus of tiny viscoelastic wires is presented. The important mechanical parameters of the polydioxanone filament were obtained: the median Young's modulus was [Formula: see text] = 958 (922, 974) MPa and the shear modulus was [Formula: see text] = 357 (185, 387) MPa, resulting in a Poisson's ratio of ν = 0.34. The SX-ELLA stents exhibited significant force relaxation due to the stress relaxation of the polydioxanone monofilament, approximately 19% and 36% 10 min and 48 h after stent application, respectively. However, these results were expected, and the manufacturer and implanting clinician should be aware of the known behavior of these biodegradable materials. If possible, a biodegradable stent should be designed considering therapeutic force rather than initial force. Additionally, new and more advanced biodegradable shape-memory polymers should be considered for future study and use.
650    12
$a vstřebatelné implantáty $7 D020341
650    _2
$a biokompatibilní materiály $x chemie $7 D001672
650    _2
$a modul pružnosti $7 D055119
650    _2
$a lidé $7 D006801
650    _2
$a testování materiálů $7 D008422
650    _2
$a mechanické jevy $7 D055595
650    _2
$a polydioxanon $x chemie $7 D016687
650    _2
$a protézy - design $7 D011474
650    12
$a stenty $7 D015607
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Hosszu, Tomas $u Department of Neurosurgery, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
700    1_
$a Hromadko, Ludek $u Center of Materials and Nanotechnologies, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic. Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic.
700    1_
$a Olmrova Zmrhalova, Zuzana $u Center of Materials and Nanotechnologies, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic.
700    1_
$a Kopecek, Martin $u Department of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
700    1_
$a Smutný, Martin, $u Department of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic. $d 1989- $7 xx0300942
700    1_
$a Selke Krulichova, Iva $u Department of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
700    1_
$a Macák, Jan, $u Center of Materials and Nanotechnologies, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic. Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic. $d 1979- $7 xx0277890
700    1_
$a Kremlacek, Jan $u Department of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
773    0_
$w MED00180950 $t PloS one $x 1932-6203 $g Roč. 15, č. 7 (2020), s. e0235842
856    41
$u https://pubmed.ncbi.nlm.nih.gov/32639989 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20201125 $b ABA008
991    __
$a 20230428085537 $b ABA008
999    __
$a ok $b bmc $g 1599039 $s 1115580
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 15 $c 7 $d e0235842 $e 20200708 $i 1932-6203 $m PLoS One $n PLoS One $x MED00180950
LZP    __
$a Pubmed-20201125

Najít záznam

Citační ukazatele

Možnosti archivace