• Je něco špatně v tomto záznamu ?

Do Rural Second Homes Shape Commensal Microbiota of Urban Dwellers? A Pilot Study among Urban Elderly in Finland

M. Saarenpää, MI. Roslund, R. Puhakka, M. Grönroos, A. Parajuli, N. Hui, N. Nurminen, OH. Laitinen, H. Hyöty, O. Cinek, A. Sinkkonen, . The Adele Research Group

. 2021 ; 18 (7) : . [pub] 20210402

Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc21018873

According to the hygiene and biodiversity hypotheses, increased hygiene levels and reduced contact with biodiversity can partially explain the high prevalence of immune-mediated diseases in developed countries. A disturbed commensal microbiota, especially in the gut, has been linked to multiple immune-mediated diseases. Previous studies imply that gut microbiota composition is associated with the everyday living environment and can be modified by increasing direct physical exposure to biodiverse materials. In this pilot study, the effects of rural-second-home tourism were investigated on the gut microbiota for the first time. Rural-second-home tourism, a popular form of outdoor recreation in Northern Europe, North America, and Russia, has the potential to alter the human microbiota by increasing exposure to nature and environmental microbes. The hypotheses were that the use of rural second homes is associated with differences in the gut microbiota and that the microbiota related to health benefits are more diverse or common among the rural-second-home users. Based on 16S rRNA Illumina MiSeq sequencing of stool samples from 10 urban elderly having access and 15 lacking access to a rural second home, the first hypothesis was supported: the use of rural second homes was found to be associated with lower gut microbiota diversity and RIG-I-like receptor signaling pathway levels. The second hypothesis was not supported: health-related microbiota were not more diverse or common among the second-home users. The current study encourages further research on the possible health outcomes or causes of the observed microbiological differences. Activities and diet during second-home visits, standard of equipment, surrounding environment, and length of the visits are all postulated to play a role in determining the effects of rural-second-home tourism on the gut microbiota.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc21018873
003      
CZ-PrNML
005      
20210830100446.0
007      
ta
008      
210728s2021 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/ijerph18073742 $2 doi
035    __
$a (PubMed)33918486
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Saarenpää, Mika $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
245    10
$a Do Rural Second Homes Shape Commensal Microbiota of Urban Dwellers? A Pilot Study among Urban Elderly in Finland / $c M. Saarenpää, MI. Roslund, R. Puhakka, M. Grönroos, A. Parajuli, N. Hui, N. Nurminen, OH. Laitinen, H. Hyöty, O. Cinek, A. Sinkkonen, . The Adele Research Group
520    9_
$a According to the hygiene and biodiversity hypotheses, increased hygiene levels and reduced contact with biodiversity can partially explain the high prevalence of immune-mediated diseases in developed countries. A disturbed commensal microbiota, especially in the gut, has been linked to multiple immune-mediated diseases. Previous studies imply that gut microbiota composition is associated with the everyday living environment and can be modified by increasing direct physical exposure to biodiverse materials. In this pilot study, the effects of rural-second-home tourism were investigated on the gut microbiota for the first time. Rural-second-home tourism, a popular form of outdoor recreation in Northern Europe, North America, and Russia, has the potential to alter the human microbiota by increasing exposure to nature and environmental microbes. The hypotheses were that the use of rural second homes is associated with differences in the gut microbiota and that the microbiota related to health benefits are more diverse or common among the rural-second-home users. Based on 16S rRNA Illumina MiSeq sequencing of stool samples from 10 urban elderly having access and 15 lacking access to a rural second home, the first hypothesis was supported: the use of rural second homes was found to be associated with lower gut microbiota diversity and RIG-I-like receptor signaling pathway levels. The second hypothesis was not supported: health-related microbiota were not more diverse or common among the second-home users. The current study encourages further research on the possible health outcomes or causes of the observed microbiological differences. Activities and diet during second-home visits, standard of equipment, surrounding environment, and length of the visits are all postulated to play a role in determining the effects of rural-second-home tourism on the gut microbiota.
650    _2
$a senioři $7 D000368
650    _2
$a lidé $7 D006801
650    12
$a mikrobiota $7 D064307
650    _2
$a pilotní projekty $7 D010865
650    _2
$a RNA ribozomální 16S $x genetika $7 D012336
651    _2
$a Evropa $7 D005060
651    _2
$a Finsko $7 D005387
651    _2
$a Severní Amerika $7 D009656
651    _2
$a Rusko $7 D012426
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Roslund, Marja I $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
700    1_
$a Puhakka, Riikka $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
700    1_
$a Grönroos, Mira $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland
700    1_
$a Parajuli, Anirudra $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland $u Department of Medicine, Karolinska University Hospital, Huddinge, 141 86 Stockholm, Sweden
700    1_
$a Hui, Nan $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland $u School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan RD. Minhang District, Shanghai 200240, China
700    1_
$a Nurminen, Noora $u Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland
700    1_
$a Laitinen, Olli H $u Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland
700    1_
$a Hyöty, Heikki $u Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland
700    1_
$a Cinek, Ondrej $u Second Faculty of Medicine, Charles University, V Úvalu 84, 150 06 Prague 5, Czech Republic
700    1_
$a Sinkkonen, Aki $u Ecosystems and Environment Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Niemenkatu 73, 15140 Lahti, Finland $u Natural Resources Institute Finland, Itäinen Pitkäkatu 4 A, 20520 Turku, Finland
700    1_
$a The Adele Research Group,
773    0_
$w MED00176090 $t International journal of environmental research and public health $x 1660-4601 $g Roč. 18, č. 7 (2021)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/33918486 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y p $z 0
990    __
$a 20210728 $b ABA008
991    __
$a 20210830100446 $b ABA008
999    __
$a ok $b bmc $g 1689841 $s 1139319
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2021 $b 18 $c 7 $e 20210402 $i 1660-4601 $m International journal of environmental research and public health $n Int. j. environ. res. public health $x MED00176090
LZP    __
$a Pubmed-20210728

Najít záznam

Citační ukazatele

Možnosti archivace