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Endometriosis and gynaecological cancers: molecular insights behind a complex machinery

V. Vetvicka, L. Fiala, S. Garzon, G. Buzzaccarini, M. Terzic, AS. Laganà

. 2021 ; 20 (4) : 201-206. [pub] 20211206

Jazyk angličtina Země Polsko

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc22010464

Endometriosis is described as the presence of both endometrial glandular and stromal cells outside the uterine cavity. A major characterization of this disease is ectopic implantation of endometrial cells with increased migration. It is one of the leading causes of morbidity among premenopausal women, with a prevalence of 10-16% of women of reproductive age. Despite over century of intensive research, none of the current treatment options represents a real cure. Based on the current knowledge, endometriosis, particularly its atypical version, is considered to be a transitional form from benign disease to tumour. However, the exact mechanisms of this conversion are still not fully established.

Citace poskytuje Crossref.org

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