PURPOSE: The aim of this study was to report intermediate-term results of duplex ultrasound follow-up of carotid artery stenting performed with the dual-layer stent as compared to concurrent patients treated with other commercially available single-layer carotid stents. MATERIALS AND METHODS: A single centre, retrospective, nonrandomized study including 162 non-consecutive patients with 199 implanted carotid stents treated over a 7-year period was conducted. Patients with at least one ultrasound examination after treatment were included. Procedural and follow-up data for patients treated with the dual-layer stent implantation (83 stents) vs first-generation carotid stents implantations (116 stents) were compared. RESULTS: The median follow-up time was 24.0 months (IQR 10-32 months) for dual-layer stents and 27.5 months (IQR 10.3-59 months) for single-layer stents. The rate of severe restenosis was significantly higher in the dual-layer stent group than in the single-layer group (13.3% [11/83] vs 3.4% [4/116], p = 0.01). Seven reinterventions were performed in 5 patients with dual-layer stents. The rate of reintervention was significantly higher compared to no reinterventions in single-layer stents (6% [5/83] vs 0% [0/116], p = 0.012). Patients with restenosis had significantly higher presence of dyslipidaemia (100% [12/12] vs 63.3% [95/150], p = 0.009). CONCLUSIONS: In this real-world cohort of patients undergoing carotid artery stenting, the patients treated with low-profile dual-layer micromesh stent showed higher rates of restenosis and reinterventions compared to first-generation single-layer stents.

Clinic of Neurology University Hospital Kollárova 2 036 59 Martin Slovakia

Clinic of Radiology Comenius University's Jessenius Faculty of Medicine and University Hospital Kollárova 2 036 59 Martin Slovakia

Department of Geotechnics Faculty of Civil Engineering University of Žilina Univerzitná 8215 1 010 26 Žilina Slovakia

Department of Medical Biophysics Faculty of Medicine and Dentistry Palacký University Olomouc Hněvotínská 976 3 775 15 Olomouc Czech Republic

Department of Radiology Faculty of Medicine and Dentistry Palacky University Olomouc 1 P Pavlova 185 6 77520 Olomouc Czech Republic

Department of Vascular Surgery University Hospital Kollárova 2 036 59 Martin Slovakia

Diagnostic and Interventional Neuroradiology University Medical Center Hamburg Eppendorf 20251 Hamburg Germany

Middle Slovak Institute of Cardiovascular Diseases Cesta k nemocnici 1 974 01 Banská Bystrica Slovakia

Orthopedic Clinic Comenius University's Jessenius Faculty of Medicine and University Hospital Kollárova 2 036 59 Martin Slovakia

Vaša Ambulancia s r o Prieložtek 1 036 01 Martin Slovakia

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