• Je něco špatně v tomto záznamu ?

Predictors of symptomatic intracerebral hemorrhage after endovascular treatment for acute ischemic stroke due to tandem lesion in anterior circulation

R. Havlíček, D. Šaňák, D. Černík, J. Neradová, N. Leško, Z. Gdovinová, M. Köcher, F. Cihlář, J. Malik, J. Fedorko, P. Pedowski, J. Zapletalová

. 2024 ; 33 (9) : 107852. [pub] 20240708

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, multicentrická studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc24019114

BACKGROUND: Endovascular treatment (EVT) of tandem lesion (TL) in the anterior circulation acute ischemic stroke (IS) usually requires periprocedural antithrombotic treatment and early initiation of dual antiplatelet therapy (DAPT) after carotid stenting. However, it may contribute to an occurrence of symptomatic intracerebral hemorrhage (SICH) in some cases. We investigated factors influencing the SICH occurrence and assessed the possible predictors of SICH after EVT. METHODS: IS patients with TL in the anterior circulation treated with EVT were enrolled in the multicenter retrospective ASCENT study. A good three-month clinical outcome was scored as 0-2 points in modified Rankin Scale (mRS) and recanalization using the TICI scale. SICH was assessed using the SITS-MOST criteria. Logistic regression analysis was used for the assessment of possible predictors of SICH with adjustment for potential confounders. RESULTS: In total, 300 (68.7 % males, mean age 67.3 ± 10.2 years) patients with median of admission NIHSS 17 were analyzed. Recanalization (TICI 2b-3) was achieved in 290 (96.7 %) patients and 176 (58.7 %) had mRS 0-2. SICH occurred in 25 (8.3 %) patients. Patients with SICH did not differ from those without SICH in the rate of periprocedural antithrombotic treatment (64 vs. 57.5 %, p = 0.526) and in the rate of DAPT started within the first 12 h after EVT (20 vs. 42.2 %, p = 0.087). After adjustment, admission NIHSS and admission glycemia were found as the only predictors of SICH after EVT. CONCLUSION: Admission NIHSS and glycemia were found as the only predictors of SICH after EVT for TL. No associations between periprocedural antithrombotic treatment, early start of DAPT after EVT and SICH occurrence were found.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24019114
003      
CZ-PrNML
005      
20241024111558.0
007      
ta
008      
241015s2024 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.jstrokecerebrovasdis.2024.107852 $2 doi
035    __
$a (PubMed)38986970
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Havlíček, Roman $u Comprehensive Stroke Center, Department of Neurology, Palacký University Medical School and University Hospital Olomouc, Czech Republic; Comprehensive Stroke Center, Department of Neurology, Central Military Hospital Prague, Czech Republic
245    10
$a Predictors of symptomatic intracerebral hemorrhage after endovascular treatment for acute ischemic stroke due to tandem lesion in anterior circulation / $c R. Havlíček, D. Šaňák, D. Černík, J. Neradová, N. Leško, Z. Gdovinová, M. Köcher, F. Cihlář, J. Malik, J. Fedorko, P. Pedowski, J. Zapletalová
520    9_
$a BACKGROUND: Endovascular treatment (EVT) of tandem lesion (TL) in the anterior circulation acute ischemic stroke (IS) usually requires periprocedural antithrombotic treatment and early initiation of dual antiplatelet therapy (DAPT) after carotid stenting. However, it may contribute to an occurrence of symptomatic intracerebral hemorrhage (SICH) in some cases. We investigated factors influencing the SICH occurrence and assessed the possible predictors of SICH after EVT. METHODS: IS patients with TL in the anterior circulation treated with EVT were enrolled in the multicenter retrospective ASCENT study. A good three-month clinical outcome was scored as 0-2 points in modified Rankin Scale (mRS) and recanalization using the TICI scale. SICH was assessed using the SITS-MOST criteria. Logistic regression analysis was used for the assessment of possible predictors of SICH with adjustment for potential confounders. RESULTS: In total, 300 (68.7 % males, mean age 67.3 ± 10.2 years) patients with median of admission NIHSS 17 were analyzed. Recanalization (TICI 2b-3) was achieved in 290 (96.7 %) patients and 176 (58.7 %) had mRS 0-2. SICH occurred in 25 (8.3 %) patients. Patients with SICH did not differ from those without SICH in the rate of periprocedural antithrombotic treatment (64 vs. 57.5 %, p = 0.526) and in the rate of DAPT started within the first 12 h after EVT (20 vs. 42.2 %, p = 0.087). After adjustment, admission NIHSS and admission glycemia were found as the only predictors of SICH after EVT. CONCLUSION: Admission NIHSS and glycemia were found as the only predictors of SICH after EVT for TL. No associations between periprocedural antithrombotic treatment, early start of DAPT after EVT and SICH occurrence were found.
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a senioři $7 D000368
650    12
$a endovaskulární výkony $x škodlivé účinky $x přístrojové vybavení $7 D057510
650    _2
$a retrospektivní studie $7 D012189
650    12
$a cerebrální krvácení $x diagnostické zobrazování $x etiologie $x terapie $7 D002543
650    _2
$a lidé středního věku $7 D008875
650    _2
$a výsledek terapie $7 D016896
650    _2
$a rizikové faktory $7 D012307
650    12
$a ischemická cévní mozková příhoda $x etiologie $x terapie $x diagnóza $x diagnostické zobrazování $7 D000083242
650    _2
$a časové faktory $7 D013997
650    12
$a inhibitory agregace trombocytů $x škodlivé účinky $x aplikace a dávkování $7 D010975
650    12
$a fibrinolytika $x aplikace a dávkování $x škodlivé účinky $7 D005343
650    12
$a posuzování pracovní neschopnosti $7 D004185
650    _2
$a hodnocení rizik $7 D018570
650    _2
$a stenty $7 D015607
650    _2
$a senioři nad 80 let $7 D000369
650    _2
$a duální protidestičková léčba $x škodlivé účinky $7 D000080903
651    _2
$a Japonsko $7 D007564
655    _2
$a časopisecké články $7 D016428
655    _2
$a multicentrická studie $7 D016448
700    1_
$a Šaňák, Daniel $u Comprehensive Stroke Center, Department of Neurology, Palacký University Medical School and University Hospital Olomouc, Czech Republic. Electronic address: daniel.sanak@centrum.cz
700    1_
$a Černík, David $u Comprehensive Stroke Center, Department of Neurology, Masaryk Hospital, KZ a.s., Ústí nad Labem, Czech Republic
700    1_
$a Neradová, Jarmila $u Comprehensive Stroke Center, Department of Neurology, Masaryk Hospital, KZ a.s., Ústí nad Labem, Czech Republic
700    1_
$a Leško, Norbert $u Department of Neurology, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia
700    1_
$a Gdovinová, Zuzana $u Department of Neurology, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia
700    1_
$a Köcher, Martin $u Department of Neurology, Palacký University Medical School and University Hospital Olomouc, Czech Republic
700    1_
$a Cihlář, Filip $u Department of Radiology, J. E. Purkinje University, Masaryk Hospital, KZ a.s., Ústí nad Labem, Czech Republic
700    1_
$a Malik, Jozef $u Department of Radiology, Central Military Hospital Prague, Czech Republic
700    1_
$a Fedorko, Jakub $u Department of Radiodiagnostics and Imaging techniques, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia
700    1_
$a Pedowski, Piotr $u Department of Radiodiagnostics and Imaging techniques, P.J. Šafarik University, Faculty of Medicine and University Hospital L. Pasteur Košice, Slovakia
700    1_
$a Zapletalová, Jana $u Department of Biophysics and Statistics, Palacký University Medical School Olomouc, Czech Republic
773    0_
$w MED00167194 $t Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association $x 1532-8511 $g Roč. 33, č. 9 (2024), s. 107852
856    41
$u https://pubmed.ncbi.nlm.nih.gov/38986970 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20241015 $b ABA008
991    __
$a 20241024111552 $b ABA008
999    __
$a ok $b bmc $g 2201751 $s 1231087
BAS    __
$a 3
BAS    __
$a PreBMC-MEDLINE
BMC    __
$a 2024 $b 33 $c 9 $d 107852 $e 20240708 $i 1532-8511 $m Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association $n J Stroke Cerebrovasc Dis $x MED00167194
LZP    __
$a Pubmed-20241015

Najít záznam

Citační ukazatele

Možnosti archivace