Circular dichroism studies of salt- and alcohol- induced conformational changes in cyanophage S-2L DNA which contains amino 2 adenine instead of adenine
Language English Country England, Great Britain Media print
Document type Journal Article
- MeSH
- Adenine chemistry MeSH
- Bacteriophages genetics MeSH
- Cesium MeSH
- Sodium Chloride MeSH
- Chlorides * MeSH
- Circular Dichroism MeSH
- DNA, Viral chemistry MeSH
- Ethanol MeSH
- Nucleic Acid Conformation MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Adenine MeSH
- cesium chloride MeSH Browser
- Cesium MeSH
- Sodium Chloride MeSH
- Chlorides * MeSH
- DNA, Viral MeSH
- Ethanol MeSH
DNA molecules containing AT pairs exhibit cesium cation specific conformational behavior. This specificity is shown to be cancelled with the title DNA, which not only concerns its conformational alterations in high-salt aqueous solutions but also the B-to-A transition induced by ethanol. S-2L DNA easily adopts the A-conformation in the presence of millimolar concentrations of CsCl which completely destabilize the A-conformation in calf thymus DNA. The present results demonstrate that the specific effects of cesium cations on DNA are connected with their binding to the AT pairs in the DNA minor groove.
References provided by Crossref.org
Conformational transitions of alternating purine-pyrimidine DNAs in perchlorate ethanol solutions
