Circular dichroism studies of salt- and alcohol- induced conformational changes in cyanophage S-2L DNA which contains amino 2 adenine instead of adenine
Jazyk angličtina Země Velká Británie, Anglie Médium print
Typ dokumentu časopisecké články
- MeSH
- adenin chemie MeSH
- bakteriofágy genetika MeSH
- cesium MeSH
- chlorid sodný MeSH
- chloridy * MeSH
- cirkulární dichroismus MeSH
- DNA virů chemie MeSH
- ethanol MeSH
- konformace nukleové kyseliny MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- adenin MeSH
- cesium chloride MeSH Prohlížeč
- cesium MeSH
- chlorid sodný MeSH
- chloridy * MeSH
- DNA virů MeSH
- ethanol MeSH
DNA molecules containing AT pairs exhibit cesium cation specific conformational behavior. This specificity is shown to be cancelled with the title DNA, which not only concerns its conformational alterations in high-salt aqueous solutions but also the B-to-A transition induced by ethanol. S-2L DNA easily adopts the A-conformation in the presence of millimolar concentrations of CsCl which completely destabilize the A-conformation in calf thymus DNA. The present results demonstrate that the specific effects of cesium cations on DNA are connected with their binding to the AT pairs in the DNA minor groove.
Citace poskytuje Crossref.org
Conformational transitions of alternating purine-pyrimidine DNAs in perchlorate ethanol solutions
