Isolation method for lysine-excreting mutants of Arthrobacter globiformis
Folia microbiologica.
1991 ;
36 (1) :
67-70.
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
Persistent link
https://www.medvik.cz/link/pmid01841851
PubMed
1841851
DOI
10.1007/bf02935824
Knihovny.cz E-resources
- MeSH
- Alanine biosynthesis MeSH
- Drug Resistance, Microbial genetics MeSH
- Arthrobacter genetics isolation & purification metabolism MeSH
- Bacteriological Techniques MeSH
- Cysteine analogs & derivatives pharmacology MeSH
- Lysine biosynthesis MeSH
- Methylnitronitrosoguanidine MeSH
- Mutation MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Alanine MeSH
- Cysteine MeSH
- Lysine MeSH
- Methylnitronitrosoguanidine MeSH
- S-2-aminoethyl cysteine MeSH Browser
To improve the yield of lysine by the isolate, auxotrophic mutants were isolated. Among the mutants, only one auxotrophic mutant required vitamin B12. This mutant produced alpha-alanine. About 200 mutants resistant to the lysine analog S-(2-aminoethyl)-L-cysteine were isolated and some of them produced well above the wild type.
