The corpus of bioinformatics resources is huge and expanding rapidly, presenting life scientists with a growing challenge in selecting tools that fit the desired purpose. To address this, the European Infrastructure for Biological Information is supporting a systematic approach towards a comprehensive registry of tools and databases for all domains of bioinformatics, provided under a single portal (https://bio.tools). We describe here the practical means by which scientific communities, including individual developers and projects, through major service providers and research infrastructures, can describe their own bioinformatics resources and share these via bio.tools.

CEITEC Central European Institute of Technology Masaryk University Brno Kamenice 5 625 00 Brno Bohunice Czech Republic

Center for Proteomics and Metabolomics Leiden University Medical Center Leiden Netherlands

Computational Biology Unit Department of Informatics University of Bergen N 5020 Bergen Norway

Department of Biochemistry and Molecular Biology and VILLUM Center for Bioanalytical Sciences University of Southern Denmark Campusvej 55 5230 Odense Denmark

Department of Information and Computing Sciences Utrecht University Utrecht Netherlands

ELIXIR EE Institute of Computer Science University of Tartu J Liivi 2 Tartu Estonia

ELIXIR Hub Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SD United Kingdom

Faculty of Informatics Masaryk University Botanická 68a 602 00 Brno Czech Republic

Hub de Bioinformatique et Biostatistique Département Biologie Computationnelle Institut Pasteur USR 3756 CNRS Paris France

National Life Science Supercomputing Center Technical University of Denmark Building 208 DK 2800 Kongens Lyngby Denmark

Novo Nordisk Foundation Center for Protein Research Faculty of Health and Medical Sciences University of Copenhagen

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The bio.tools registry of software tools and data resources for the life sciences