Hladiny solubilního receptoru pro interleukin-2 v séru nemocných s revmatoidní artritidou
[Levels of soluble receptors for interleukin-2 in the serum of patients with rheumatoid arthritis]

. 1990 Dec 14 ; 129 (50) : 1582-5.

Jazyk čeština Země Česko Médium print

Typ dokumentu anglický abstrakt, časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/pmid02272075
Odkazy

PubMed 2272075

The authors assessed, using the method of sandwich enzyme immunoassay (ELISA), the soluble receptor for interleukin-2 (s-r IL-2). In patients with rheumatoid arthritis mean values of 620.5 = 500.0 u./ml were recorded which was significantly higher than in patients with osteoarthritis (p less than 0.001) (313.3 +/- 155 n./ml) and in healthy controls (181.7 +/- 159.6 n./ml). In patients with rheumatoid arthritis a correlation was found between the activity of the disease expressed by means of Lansbury's index (r = 0.61, p less than 0.01). There was no correlation between s-r IL-2 and the sedimentation rate (r = 0.32, p = n. s.). The author reviews the literature and discusses the hypothesis that s-r IL-2 acts as a competitive inhibitor for interleukin-2.

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