All 91,823 children born in 1980 in Bohemia (population 6.314 million; area 52,478 square kilometers) were examined at least four times during infancy and at the age of three and four years. All children who died were autopsied and those with heart disease were selected. A total of 779 children (8.223/1000 live births) were suspected by provincial pediatric cardiologists of having a heart disease. All of these were examined at the age of four years at our Center of Pediatric Cardiology. At this age heart disease was proved in 613 alive or deceased children (6.676/1000 live births), congenital cardiac malformations in 589 (6.415/1000 live births), and cardiomyopathies in 24. The most frequent congenital heart defects (CHD) were ventricular septal defect (VSD) (31.41%), atrial septal defect (ASD) (11.37%), aortic stenosis (AS) (7.64%), pulmonary stenosis (PS) (7.13%), coarctation of the aorta (CoA) (5.77%), and transposition of the great arteries (TGA) (5.43%), followed by persistent ductus arteriosus (PDA) (4.75%), atrioventricular septal defect (AVSD) and hypoplastic left heart syndrome (HLHS) (4.07% each), tetralogy of Fallot (TF) (3.56%), and pulmonary atresia (PA) (2.38%). A prevalence of less than 0.1/1000 live births was found for the remaining cardiovascular defects. One hundred fifty-nine (25.9%) patients were admitted to our highly specialized center, 116 (19.7%) catheterized and 85 (13.9%) treated surgically, during the first four years of life. A total of 440 (71.8%) patients survived the fourth year of life. The percentage of deaths was 25.6% among those with congenital heart diseases and 71% with cardiomyopathies. The overall mortality rate was 27% in surgically and 26% in medically treated patients.

Center of Pediatric Cardiology and Cardiovascular Surgery University Hospital Motol Prague Czechoslovakia

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Pediatrics. 1955 Jan;15(1):12-32 PubMed

Br Heart J. 1981 Jul;46(1):55-62 PubMed

Int J Cardiol. 1986 Apr;11(1):63-74 PubMed

Am J Obstet Gynecol. 1965 Jan 1;91:37-45 PubMed

Br Heart J. 1959 Jan;21(1):40-50 PubMed

Cor Vasa. 1981;23(1):1-3 PubMed

Br Med J. 1960 Jan 30;1(5169):309-15 PubMed

Can Med Assoc J. 1964 Jul 18;91:95-100 PubMed

Br Heart J. 1977 Apr;39(4):445-50 PubMed

Br Heart J. 1970 May;32(3):304-6 PubMed

Am J Hum Genet. 1958 Dec;10(4):398-445 PubMed

Can Med Assoc J. 1964 Aug 22;91:365-71 PubMed

Mayo Clin Proc. 1971 Dec;46(12):794-9 PubMed

Major heart defects: the diagnostic evaluations of first-year-olds

Boy:girl ratio in children born with different forms of cardiac malformation: a population-based study

Children with congenital heart disease: probability of natural survival