Production of rhodomycins in Streptomyces griseoruber 4620
Language English Country United States Media print
Document type Journal Article
PubMed
7439844
DOI
10.1007/bf02897211
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents biosynthesis isolation & purification MeSH
- Anthracyclines MeSH
- Naphthacenes biosynthesis isolation & purification MeSH
- Streptomyces metabolism MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Anthracyclines MeSH
- Naphthacenes MeSH
- rhodomycin MeSH Browser
The strain Streptomyces griseoruber 4620 produces, besides the anthracycline antibiotics beromycins, some other anthracyclines of the rhodomycin type. Twelve isolates exhibiting a higher antibiotic activity (up to 2.5X), as compared to the parent strain, were obtained after a spontaneous selection. The following species were isolated from the hydrolysate of mycelial extract: beta-rhodomycinone, beta-isorhodomycinone, alpha 2-rhodomycinone, epsilon-rhodomycinone and 10-deoxy-beta-rhodomycinone, which has not yet been described.
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