Podtriedy IgG u detí s recidivujúcimi respiracnými chorobami
[IgG subclasses in children with recurrent respiratory diseases]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
8137441
- MeSH
- Child MeSH
- Enzyme-Linked Immunosorbent Assay MeSH
- Immunoglobulin G analysis classification MeSH
- Humans MeSH
- Adolescent MeSH
- Respiratory Tract Diseases immunology MeSH
- Child, Preschool MeSH
- Recurrence MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Adolescent MeSH
- Child, Preschool MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Immunoglobulin G MeSH
The authors examined IgG sub-classes, using the ELISA method, in 35 patients with relapsing respiratory diseases and 27 children of a control group aged 3-15 years. In children with relapsing respiratory diseases without deficiency of the main immunoglobulin classes they found a statistically significantly reduced value in sub-class IgG2 (P < or = 0.01). The changes found in other sub-classes were not statistically significant. The authors draw attention to the fact that deficiency in IgG sub-classes should be considered in case of repeated respiratory infections caused by encapsulated microorganisms--H. influenzae, Str. pneumoniae--and also when reduced levels of IgG and IgA are found. However, even normal levels do not rule out deficiency.
