Therapy of hypertension is still more or less empirical. Several classes of antihypertensive medications are known, the effect of which is based on different mechanisms. The efficacy of the treatment is not always a reliable indication of the appropriate selection as a good therapeutical response can sometimes be achieved at the expense of humoral simulation. This can lead to harmful increased synthesis of trophic hormones. The program for PC called HYPERTENZE supports decision making in therapy of arterial hypertension. It gives a sequence of decisions based on clinical experience using a series of parameters. The program is using the Microsoft Access language of the Access database system and due to the Access Developers Toolkit it does not require Access to be installed on the user's computer. The program HYPERTENZE offers the user essential information and explanation of the decisions in a graded form. The price list of equivalent medications can be updated by the user himself. It seems that this program might be very useful for Czech general practitioners.

2nd Department of Medicine 1st Faculty of Medicine Prague Czech Republic

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