Antimutagenicity of milk fermented by Enterococcus faecium
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
10997133
DOI
10.1007/bf02816252
Knihovny.cz E-resources
- MeSH
- Acrylates toxicity MeSH
- Antimutagenic Agents pharmacology MeSH
- Enterococcus faecium metabolism MeSH
- Euglena gracilis drug effects MeSH
- Fermentation MeSH
- Methylnitronitrosoguanidine toxicity MeSH
- Milk chemistry metabolism MeSH
- Mutagenesis * MeSH
- Nitrofurans toxicity MeSH
- Nitrovin toxicity MeSH
- Salmonella typhimurium drug effects MeSH
- Ultraviolet Rays MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Acrylates MeSH
- Antimutagenic Agents MeSH
- Methylnitronitrosoguanidine MeSH
- Nitrofurans MeSH
- nitrofurylacrylic acid MeSH Browser
- Nitrovin MeSH
The diethyl ether extracts isolated from unfermented milk and milk fermented by Enterococcus faecium exhibited dose-dependent inhibition of mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), nitrovin (NIT), 5-nitro-2-furylacrylic acid (NFA) and UV-irradiation on the Ames bacterial test (Salmonella typhimurium strains TA97 and TA100) and the unicellular flagellate Euglena gracilis. Overall, the fermented milk extract was the most active against UV-irradiation, less active against NIT and MNNG, and the least active against NFA on bacteria. The highest antibleaching effects were observed against MNNG. The differences between antimutagenic effects from fermented and unfermented milk extracts were determined to be statistically significant at the 0.95 CI level.
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