Hypocholesterolemic and immunostimulatory effects of orally applied Enterococcus faecium M-74 in man

. 1995 ; 40 (6) : 639-46.

Jazyk angličtina Země Spojené státy americké Médium print

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid08768254

Lyophilized Enterococcus faecium M-74 was administered to 12 adult subjects in a daily oral dose of 5 x 10(9) bacteria for six weeks. The bacterium temporarily colonized the host intestine and its excretion with stool persisted for five weeks after the last does. The mean levels of serum cholesterol and LDL showed a a biphasic effect--an elevation followed by a sharp decrease (on day 64 of investigation). The decrease corresponded in time with a significant increase in the ability to reduce iodonitrotetrazolium and superoxide production by peripheral neutrophils incubated with zymosan or phorbol myristate acetate, and also with an elevated production of IgG by peripheral blood mononuclear cells. Hence, intake of E. faecium may have a hypocholesterolemic and immunostimulatory effect. It was also demonstrated that E. faecium significantly reduced the average activity of beta-D-glucuronidase in stools.

Zobrazit více v PubMed

Biochim Biophys Acta. 1993 Aug 18;1178(2):221-7 PubMed

Immunol Lett. 1993 Dec;39(1):71-5 PubMed

Acta Pathol Jpn. 1989 Aug;39(8):473-86 PubMed

J Dairy Sci. 1984 Feb;67(2):255-62 PubMed

Atherosclerosis. 1977 Mar;26(3):335-40 PubMed

Biochemistry. 1994 Aug 23;33(33):10127-36 PubMed

FEMS Microbiol Rev. 1993 Sep;12(1-3):207-20 PubMed

J Pediatr Gastroenterol Nutr. 1990 Nov;11(4):509-12 PubMed

J Biol Chem. 1959 Jun;234(6):1355-62 PubMed

Biochem Biophys Res Commun. 1994 Aug 15;202(3):1300-7 PubMed

Agents Actions. 1982 Oct;12(4):478-84 PubMed

Dig Dis Sci. 1992 Jan;37(1):121-8 PubMed

Scand J Clin Lab Invest Suppl. 1968;97:77-89 PubMed

Biochem J. 1994 Aug 15;302 ( Pt 1):297-304 PubMed

Biochem J. 1994 Jul 15;301 ( Pt 2):421-8 PubMed

Am J Clin Nutr. 1984 May;39(5):756-61 PubMed

Trends Biochem Sci. 1993 Feb;18(2):43-7 PubMed

Annu Rev Biochem. 1983;52:223-61 PubMed

Bratisl Lek Listy. 1988 Jun;89(6):424-32 PubMed

Proc Natl Acad Sci U S A. 1984 Jun;81(12):3883-7 PubMed

Biochem J. 1993 Feb 15;290 ( Pt 1):165-72 PubMed

Int J Immunopharmacol. 1990;12(6):675-84 PubMed

Nature. 1993 Apr 29;362(6423):801-9 PubMed

Infect Immun. 1989 Nov;57(11):3576-80 PubMed

Biochem Biophys Res Commun. 1988 Feb 15;150(3):1294-301 PubMed

World J Microbiol Biotechnol. 1995 May;11(3):294-8 PubMed

FEMS Microbiol Rev. 1990 Sep;7(1-2):175-88 PubMed

Microbiologica. 1992 Oct;15(4):413-7 PubMed

J Dairy Sci. 1989 Nov;72(11):2885-99 PubMed

Najít záznam

Citační ukazatele

Nahrávání dat ...

Možnosti archivace

Nahrávání dat ...