Occurrence and transferability of beta-lactam resistance in Enterobacteriaceae isolated in Children's University Hospital in Bratislava
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
11830947
DOI
10.1007/bf02815624
Knihovny.cz E-zdroje
- MeSH
- antibakteriální látky farmakologie MeSH
- beta-laktamasy genetika MeSH
- beta-laktamová rezistence genetika MeSH
- beta-laktamy farmakologie MeSH
- ceftazidim farmakologie MeSH
- Enterobacteriaceae účinky léků enzymologie genetika MeSH
- enterobakteriální infekce epidemiologie mikrobiologie MeSH
- kojenec MeSH
- konjugace genetická MeSH
- lidé MeSH
- mikrobiální testy citlivosti MeSH
- nemocnice univerzitní * MeSH
- novorozenec MeSH
- plazmidy genetika MeSH
- předškolní dítě MeSH
- Check Tag
- kojenec MeSH
- lidé MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Slovenská republika epidemiologie MeSH
- Názvy látek
- antibakteriální látky MeSH
- beta-laktamasy MeSH
- beta-laktamy MeSH
- ceftazidim MeSH
Occurrence and transferability of beta-lactam resistance in 30 multi-resistant Escherichia coli, Klebsiella spp., Enterobacter spp., Pantoea agglomerans, Citrobacter freundii and Serratia marcescens strains isolated from children between 0 and 3 years of age is presented. The strains were resistant to ampicillin (30), cefoxitin (22), cefotaxime (30), ceftriaxone (30), ceftazidime (30) and aztreonam (28), but susceptible to cefepime (30) and imipenem (26). Twenty-eight of 30 isolates possessed a transferable resistance confirmed by conjugation and isolation of 79-89-kb plasmids. The beta-lactam resistance was due to production of beta-lactamases and ceftazidime proved to be stronger beta-lactamase inductor than ceftriaxone. Twenty-five clinical isolates expressed transferable extended spectrum beta-lactamases, and chromosomally encoded AmpC beta-lactamase.
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